INSMED Inc
INSM · Pharmaceutical Preparations · 216.8M shares · +14%/yr ↑ shares · EDGAR filings ↗
Reference price $102.34 · est. market cap ~$22.2B — last insider sale, 2026-06-25 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)
Grade
D50Rare-disease biotech at a major launch (brensocatib) with enormous cash burn but funded.
Strengths
- High gross margin, marketed Arikayce — gross margin 80%
- Adequate liquidity — current ratio 3.8 (50th)
Risks
- Enormous cash burn — FCF -$968M (0th)
- Large pre-/early-commercial losses — operating margin -206%
- Launch-execution & funding/leverage risk — per 10-K
Notable findings
- No interest coverageInterest coverage -14.88 (cannot cover interest)
- Cash burnNegative free cash flow (-967.6M)
- Fund exitedNotable fund(s) exited this quarter: VANGUARD GROUP INC
- Exec changeRecent 8-K item 5.02 8-K ↗
- Net lossNet loss (net margin -210.5%)
- Insider sellingInsider selling — 116 open-market sale(s) by 6 insider(s) (cluster of 6 insiders, ~$80M, last 6mo) Form 4 ↗
- Notable holderHeld by 6 notable fund(s): FMR LLC, STATE STREET CORP, CITADEL ADVISORS LLC +3 more (as of 2026-03-31)
- New fund positionNotable fund(s) opened this quarter: Bridgewater Associates, LP
Quarterly revenue
Last 4 quarters · from SEC filings.
Key metrics
Gross margin
79.7%
Operating margin
-205.6%
Net margin
-210.5%
Return on equity
-172.8%
Return on assets
-56.4%
ROIC
-77.0%
Revenue growth (QoQ)
16.0%
Debt / equity
0.7×
Interest coverage
-14.9×
Current ratio
3.8×
Free cash flow
-$968M
Tangible book value
$505M
Cash & investments
$1.4B
Cash runway
6q
Stock comp / revenue
25.2%
Insider transactions · last 18 months
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| 2026-06-25 | Lewis William | Sell | 1.8K | $103.10 |
| 2026-06-25 | Lewis William | Sell | 3.7K | $104.28 |
| 2026-06-25 | Lewis William | Sell | 1.3K | $106.27 |
| 2026-06-25 | Lewis William | Option exercise | 13K | $30.46 |
| 2026-06-25 | Lewis William | Sell | 12K | $102.34 |
| 2026-06-25 | Lewis William | Sell | 2.5K | $105.27 |
| 2026-06-25 | Lewis William | Option exercise | 8.9K | $17.16 |
| 2026-06-23 | Butera Samuele | Grant | 7.3K | — |
| 2026-06-22 | Smith Michael Alexander | Sell | 1.8K | $95.82 |
| 2026-06-08 | Lewis William | Sell | 6.5K | $94.03 |
| 2026-06-05 | Flammer Martina M.D. | Sell | 1.9K | $103.78 |
| 2026-06-03 | Adsett Roger | Sell | 2.4K | $102.27 |
| 2026-06-03 | Flammer Martina M.D. | Sell | 2.6K | $102.27 |
| 2026-06-03 | Smith Michael Alexander | Sell | 2.2K | $102.27 |
| 2026-06-03 | Bonstein Sara | Sell | 2.4K | $102.27 |
| 2026-06-03 | Lewis William | Sell | 7.6K | $102.27 |
| 2026-05-22 | Smith Michael Alexander | Sell | 6.1K | $108.47 |
| 2026-05-18 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-05-18 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-05-18 | Lewis William | Sell | 8.0K | $106.97 |
| 2026-05-18 | Lewis William | Sell | 5.8K | $105.32 |
| 2026-05-18 | Lewis William | Sell | 12K | $106.39 |
| 2026-05-14 | Flammer Martina M.D. | Sell | 10K | $117.54 |
| 2026-05-13 | Bonstein Sara | Sell | 8.3K | $116.18 |
| 2026-05-13 | Lewis William | Sell | 13K | $116.18 |
| 2026-05-13 | SCHAFER CAROL | Grant | 3.3K | — |
| 2026-05-13 | Smith Michael Alexander | Sell | 4.1K | $116.18 |
| 2026-05-13 | Brennan David R | Grant | 3.3K | — |
| 2026-05-13 | SHAROKY MELVIN MD | Grant | 3.3K | — |
| 2026-05-13 | Flammer Martina M.D. | Sell | 4.5K | $112.76 |
| 2026-05-13 | Flammer Martina M.D. | Sell | 3.4K | $116.18 |
| 2026-05-13 | Desjardins Clarissa | Grant | 3.3K | — |
| 2026-05-13 | ANDERSON ELIZABETH M | Grant | 3.3K | — |
| 2026-05-13 | LEE LEO | Grant | 3.3K | — |
| 2026-05-13 | Adsett Roger | Sell | 5.8K | $116.18 |
| 2026-05-11 | Flammer Martina M.D. | Sell | 830 | $101.18 |
| 2026-05-11 | Flammer Martina M.D. | Sell | 12K | $100.35 |
| 2026-05-11 | Flammer Martina M.D. | Option exercise | 13K | $17.07 |
| 2026-05-04 | Lewis William | Sell | 599 | $135.18 |
| 2026-05-04 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-05-04 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-05-04 | Lewis William | Sell | 433 | $134.18 |
| 2026-05-04 | Lewis William | Sell | 5.3K | $137.01 |
| 2026-05-04 | Lewis William | Sell | 2.7K | $137.86 |
| 2026-05-04 | Lewis William | Sell | 1.2K | $139.09 |
| 2026-05-04 | Lewis William | Sell | 381 | $139.60 |
| 2026-04-16 | Lewis William | Sell | 2.2K | $142.99 |
| 2026-04-16 | Lewis William | Sell | 5.4K | $143.81 |
| 2026-04-16 | Lewis William | Sell | 2.3K | $144.66 |
| 2026-04-16 | Lewis William | Sell | 825 | $145.79 |
| 2026-04-16 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-04-16 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-04-06 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-04-06 | Lewis William | Sell | 787 | $161.73 |
| 2026-04-06 | Lewis William | Sell | 8.5K | $163.23 |
| 2026-04-06 | Lewis William | Sell | 1.4K | $164.01 |
| 2026-04-06 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-04-01 | Adsett Roger | Option exercise | 88K | $14.56 |
| 2026-04-01 | Adsett Roger | Sell | 6.7K | $163.18 |
| 2026-04-01 | Adsett Roger | Sell | 19K | $164.11 |
| 2026-04-01 | Adsett Roger | Sell | 62K | $164.95 |
| 2026-03-30 | Smith Michael Alexander | Sell | 20K | $150.98 |
| 2026-03-30 | Smith Michael Alexander | Option exercise | 14K | $27.89 |
| 2026-03-30 | Smith Michael Alexander | Option exercise | 5.6K | $17.07 |
| 2026-03-19 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-03-19 | Lewis William | Sell | 4.5K | $143.42 |
| 2026-03-19 | Lewis William | Sell | 1.6K | $142.17 |
| 2026-03-19 | Lewis William | Sell | 4.5K | $144.11 |
| 2026-03-19 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-03-05 | Lewis William | Sell | 2.1K | $144.23 |
| 2026-03-05 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-03-05 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-03-05 | Lewis William | Sell | 2.6K | $145.27 |
| 2026-03-05 | Lewis William | Sell | 3.9K | $146.66 |
| 2026-03-05 | Lewis William | Sell | 2.1K | $147.54 |
| 2026-03-03 | SHAROKY MELVIN MD | Gift | 100 | — |
| 2026-02-25 | SHAROKY MELVIN MD | Gift | 1.1K | — |
| 2026-02-25 | SHAROKY MELVIN MD | Gift | 243 | — |
| 2026-02-25 | SHAROKY MELVIN MD | Gift | 243 | — |
| 2026-02-25 | SHAROKY MELVIN MD | Gift | 243 | — |
| 2026-02-25 | SHAROKY MELVIN MD | Gift | 243 | — |
| 2026-02-24 | Smith Michael Alexander | Option exercise | 20K | $17.07 |
| 2026-02-24 | Smith Michael Alexander | Sell | 4.2K | $155.06 |
| 2026-02-24 | Smith Michael Alexander | Sell | 16K | $156.53 |
| 2026-02-24 | Smith Michael Alexander | Sell | 4.9K | $153.93 |
| 2026-02-23 | Brennan David R | Gift | 6.0K | — |
| 2026-02-19 | Lewis William | Sell | 2.0K | $149.17 |
| 2026-02-19 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-02-19 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-02-19 | Lewis William | Sell | 1.9K | $150.10 |
| 2026-02-19 | Lewis William | Sell | 3.4K | $151.12 |
| 2026-02-19 | Lewis William | Sell | 2.4K | $151.92 |
| 2026-02-19 | Lewis William | Sell | 1.0K | $153.38 |
| 2026-02-09 | MCGIRR DAVID W J | Gift | 53K | — |
| 2026-02-09 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-02-09 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-02-09 | Lewis William | Sell | 4.9K | $147.17 |
| 2026-02-09 | Lewis William | Sell | 7.2K | $148.02 |
| 2026-02-09 | Lewis William | Sell | 1.3K | $148.83 |
| 2026-02-09 | MCGIRR DAVID W J | Gift | 53K | — |
| 2026-02-05 | Flammer Martina M.D. | Sell | 869 | $152.44 |
| 2026-02-03 | Flammer Martina M.D. | Sell | 795 | $155.77 |
| 2026-02-03 | Adsett Roger | Sell | 791 | $156.17 |
| 2026-02-03 | Bonstein Sara | Sell | 748 | $156.34 |
| 2026-02-03 | Lewis William | Sell | 3.0K | $156.34 |
| 2026-02-03 | Smith Michael Alexander | Sell | 640 | $156.27 |
| 2026-02-02 | Flammer Martina M.D. | Option exercise | 8.0K | $65.72 |
| 2026-02-02 | Flammer Martina M.D. | Sell | 563 | $152.06 |
| 2026-02-02 | Flammer Martina M.D. | Sell | 928 | $153.16 |
| 2026-02-02 | Flammer Martina M.D. | Sell | 3.3K | $154.56 |
| 2026-02-02 | Flammer Martina M.D. | Sell | 3.0K | $155.46 |
| 2026-02-02 | Flammer Martina M.D. | Sell | 100 | $156.86 |
| 2026-01-20 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-01-20 | Lewis William | Sell | 1.0K | $156.80 |
| 2026-01-20 | Lewis William | Sell | 1.2K | $158.37 |
| 2026-01-20 | Lewis William | Sell | 6.0K | $158.99 |
| 2026-01-20 | Lewis William | Sell | 2.2K | $159.85 |
| 2026-01-20 | Lewis William | Sell | 254 | $160.70 |
| 2026-01-20 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-01-12 | Lewis William | Sell | 160 | $170.24 |
| 2026-01-12 | Lewis William | Sell | 297 | $172.36 |
| 2026-01-12 | Lewis William | Sell | 315 | $174.86 |
| 2026-01-12 | Lewis William | Sell | 7.0K | $169.57 |
| 2026-01-12 | Lewis William | Sell | 7.2K | $168.63 |
| 2026-01-12 | Lewis William | Sell | 4.0K | $167.73 |
| 2026-01-12 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2026-01-12 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2026-01-12 | Lewis William | Sell | 297 | $171.31 |
| 2026-01-09 | Flammer Martina M.D. | Sell | 1.9K | $186.19 |
| 2026-01-08 | Flammer Martina M.D. | Sell | 3.3K | $174.17 |
| 2026-01-08 | Smith Michael Alexander | Sell | 1.1K | $174.17 |
| 2026-01-08 | Flammer Martina M.D. | Sell | 1.7K | $173.87 |
| 2026-01-08 | Adsett Roger | Sell | 2.1K | $174.17 |
| 2026-01-08 | Bonstein Sara | Sell | 1.4K | $174.17 |
| 2026-01-08 | Lewis William | Sell | 3.2K | $174.17 |
| 2026-01-07 | Flammer Martina M.D. | Sell | 1.4K | $175.84 |
| 2026-01-07 | Adsett Roger | Sell | 802 | $175.07 |
| 2026-01-07 | Bonstein Sara | Sell | 1.7K | $175.07 |
| 2026-01-07 | Smith Michael Alexander | Sell | 709 | $175.07 |
| 2026-01-07 | Lewis William | Sell | 2.4K | $175.07 |
| 2026-01-06 | Flammer Martina M.D. | Sell | 2.8K | $174.21 |
| 2026-01-06 | Flammer Martina M.D. | Sell | 957 | $175.01 |
| 2026-01-06 | Flammer Martina M.D. | Sell | 1.6K | $173.33 |
| 2026-01-06 | Bonstein Sara | Sell | 1.5K | $173.33 |
| 2026-01-06 | Lewis William | Sell | 4.1K | $173.33 |
| 2026-01-06 | Smith Michael Alexander | Sell | 1.4K | $173.33 |
| 2026-01-06 | Flammer Martina M.D. | Option exercise | 8.6K | $26.43 |
| 2026-01-06 | Adsett Roger | Sell | 1.4K | $173.33 |
| 2026-01-06 | Flammer Martina M.D. | Sell | 4.8K | $173.47 |
| 2026-01-05 | Flammer Martina M.D. | Sell | 1.8K | $173.45 |
| 2026-01-05 | Flammer Martina M.D. | Option exercise | 4.4K | $19.74 |
| 2026-01-05 | Flammer Martina M.D. | Option exercise | 7.9K | $29.13 |
| 2026-01-05 | Flammer Martina M.D. | Sell | 2.8K | $169.29 |
| 2026-01-05 | Flammer Martina M.D. | Sell | 3.2K | $170.61 |
| 2026-01-05 | Flammer Martina M.D. | Sell | 2.8K | $171.19 |
| 2026-01-05 | Flammer Martina M.D. | Sell | 286 | $171.92 |
| 2026-01-05 | Flammer Martina M.D. | Sell | 655 | $174.28 |
| 2026-01-05 | Flammer Martina M.D. | Sell | 702 | $175.73 |
| 2026-01-02 | Schaeffer Orlov S Nicole | Grant | 5.3K | — |
| 2026-01-02 | Schaeffer Orlov S Nicole | Sell | 34K | $175.17 |
| 2026-01-02 | Schaeffer Orlov S Nicole | Sell | 31K | $174.28 |
| 2026-01-02 | Schaeffer Orlov S Nicole | Option exercise | 87K | $13.91 |
| 2026-01-02 | Flammer Martina M.D. | Grant | 5.6K | — |
| 2026-01-02 | Adsett Roger | Grant | 6.0K | — |
| 2026-01-02 | Bonstein Sara | Grant | 6.0K | — |
| 2026-01-02 | Bonstein Sara | Grant | 5.6K | — |
| 2026-01-02 | Lewis William | Grant | 21K | — |
| 2026-01-02 | Smith Michael Alexander | Grant | 5.3K | — |
| 2026-01-02 | Flammer Martina M.D. | Grant | 6.0K | — |
| 2026-01-02 | Schaeffer Orlov S Nicole | Sell | 200 | $177.78 |
| 2026-01-02 | Schaeffer Orlov S Nicole | Sell | 9.1K | $177.17 |
| 2026-01-02 | Schaeffer Orlov S Nicole | Sell | 13K | $176.08 |
| 2025-12-18 | Lewis William | Sell | 1.4K | $167.29 |
| 2025-12-18 | Lewis William | Sell | 2.2K | $168.54 |
| 2025-12-18 | Lewis William | Sell | 1.9K | $169.58 |
| 2025-12-18 | Lewis William | Sell | 362 | $170.26 |
| 2025-12-18 | Lewis William | Sell | 51 | $171.20 |
| 2025-12-18 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2025-12-18 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2025-12-18 | Lewis William | Sell | 350 | $162.26 |
| 2025-12-18 | Lewis William | Sell | 1.5K | $163.19 |
| 2025-12-18 | Lewis William | Sell | 447 | $164.24 |
| 2025-12-18 | Lewis William | Sell | 697 | $165.21 |
| 2025-12-18 | Lewis William | Sell | 1.8K | $166.60 |
| 2025-12-05 | SHAROKY MELVIN MD | Sell | 20K | $205.01 |
| 2025-12-04 | Lewis William | Option exercise | 6.3K | $30.46 |
| 2025-12-04 | Lewis William | Option exercise | 4.4K | $17.16 |
| 2025-12-04 | Lewis William | Sell | 4.5K | $204.62 |
| 2025-12-04 | Lewis William | Sell | 2.2K | $205.66 |
| 2025-12-04 | Lewis William | Sell | 2.9K | $206.49 |
| 2025-12-04 | Lewis William | Sell | 1.0K | $207.42 |
| 2025-12-01 | Flammer Martina M.D. | Sell | 5.9K | $207.03 |
| 2025-12-01 | Flammer Martina M.D. | Option exercise | 8.9K | $25.83 |
| 2025-12-01 | Flammer Martina M.D. | Sell | 1.4K | $205.98 |
| 2025-12-01 | Flammer Martina M.D. | Sell | 1.6K | $207.73 |
| 2025-11-24 | ANDERSON ELIZABETH M | Sell | 5.0K | $204.58 |
| 2025-11-17 | LEE LEO | Sell | 18K | $194.49 |
| 2025-11-17 | LEE LEO | Sell | 15K | $195.39 |
| 2025-11-17 | LEE LEO | Sell | 3.2K | $193.51 |
| 2025-11-17 | LEE LEO | Sell | 15K | $197.40 |
| 2025-11-17 | LEE LEO | Sell | 24K | $196.61 |
| 2025-11-14 | ANDERSON ELIZABETH M | Sell | 10K | $195.87 |
| 2025-11-12 | Schaeffer Orlov S Nicole | Option exercise | 30K | $26.46 |
| 2025-11-12 | Schaeffer Orlov S Nicole | Sell | 4.1K | $192.45 |
| 2025-11-12 | Schaeffer Orlov S Nicole | Sell | 6.6K | $193.64 |
| 2025-11-12 | Schaeffer Orlov S Nicole | Sell | 19K | $194.44 |
| 2025-11-12 | Schaeffer Orlov S Nicole | Sell | 164 | $195.88 |
| 2025-11-11 | Flammer Martina M.D. | Option exercise | 13K | $17.07 |
| 2025-11-11 | Flammer Martina M.D. | Sell | 5.5K | $188.38 |
| 2025-11-11 | Flammer Martina M.D. | Option exercise | 18K | $18.95 |
| 2025-11-11 | Flammer Martina M.D. | Sell | 2.9K | $191.04 |
| 2025-11-11 | Flammer Martina M.D. | Sell | 11K | $190.33 |
| 2025-11-11 | Flammer Martina M.D. | Sell | 12K | $189.36 |
| 2025-11-06 | Brennan David R | Gift | 60K | — |
| 2025-11-06 | Brennan David R | Gift | 60K | — |
| 2025-11-03 | Smith Michael Alexander | Sell | 4.3K | $182.60 |
| 2025-11-03 | Smith Michael Alexander | Option exercise | 27K | $23.75 |
| 2025-11-03 | Smith Michael Alexander | Sell | 1.3K | $181.01 |
| 2025-11-03 | Smith Michael Alexander | Sell | 7.6K | $181.88 |
| 2025-11-03 | Smith Michael Alexander | Sell | 4.0K | $183.92 |
| 2025-11-03 | Smith Michael Alexander | Sell | 3.2K | $184.91 |
| 2025-11-03 | Smith Michael Alexander | Sell | 3.6K | $185.93 |
| 2025-11-03 | Smith Michael Alexander | Sell | 1.6K | $187.15 |
| 2025-11-03 | Smith Michael Alexander | Sell | 1.4K | $187.97 |
| 2025-09-12 | Schaeffer Orlov S Nicole | Sell | 31K | $145.67 |
| 2025-09-12 | Schaeffer Orlov S Nicole | Sell | 7.3K | $146.57 |
| 2025-09-12 | Schaeffer Orlov S Nicole | Sell | 6.2K | $147.46 |
| 2025-09-12 | SHAROKY MELVIN MD | Sell | 10K | $145.39 |
| 2025-09-12 | Schaeffer Orlov S Nicole | Option exercise | 57K | $23.75 |
| 2025-09-12 | Schaeffer Orlov S Nicole | Sell | 32K | $144.60 |
| 2025-09-11 | SHAROKY MELVIN MD | Gift | 2.0K | — |
| 2025-09-11 | SHAROKY MELVIN MD | Gift | 159 | — |
| 2025-09-11 | SHAROKY MELVIN MD | Gift | 159 | — |
| 2025-09-04 | Schaeffer Orlov S Nicole | Gift | 23K | — |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 26K | $26.43 |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 39K | $17.07 |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 13K | $19.74 |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 24K | $29.13 |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 18K | $25.83 |
| 2025-09-02 | Flammer Martina M.D. | Sell | 19K | $141.27 |
| 2025-09-02 | Flammer Martina M.D. | Sell | 5.9K | $142.03 |
| 2025-09-02 | Flammer Martina M.D. | Sell | 35K | $143.16 |
| 2025-09-02 | Flammer Martina M.D. | Sell | 28K | $144.05 |
| 2025-09-02 | Flammer Martina M.D. | Sell | 64K | $145.33 |
| 2025-09-02 | Flammer Martina M.D. | Sell | 35K | $146.05 |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 37K | $18.95 |
| 2025-09-02 | Smith Michael Alexander | Option exercise | 13K | $30.46 |
| 2025-09-02 | Smith Michael Alexander | Sell | 1.4K | $141.16 |
| 2025-09-02 | Smith Michael Alexander | Sell | 1.1K | $142.06 |
| 2025-09-02 | Smith Michael Alexander | Sell | 7.4K | $143.16 |
| 2025-09-02 | Smith Michael Alexander | Sell | 8.3K | $144.16 |
| 2025-09-02 | Smith Michael Alexander | Sell | 4.9K | $145.18 |
| 2025-09-02 | Smith Michael Alexander | Sell | 1.2K | $145.89 |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 14K | $34.03 |
| 2025-09-02 | Flammer Martina M.D. | Option exercise | 17K | $26.46 |
| 2025-08-20 | SHAROKY MELVIN MD | Sell | 10K | $129.50 |
| 2025-08-19 | Adsett Roger | Sell | 20K | $127.42 |
| 2025-08-19 | Adsett Roger | Sell | 4.8K | $128.27 |
| 2025-08-18 | Lewis William | Option exercise | 6.9K | $10.85 |
| 2025-08-18 | Lewis William | Sell | 3.0K | $127.59 |
| 2025-08-18 | Lewis William | Sell | 2.5K | $128.76 |
| 2025-08-18 | Lewis William | Sell | 1.4K | $129.47 |
| 2025-08-14 | Schaeffer Orlov S Nicole | Sell | 700 | $128.16 |
| 2025-08-14 | Schaeffer Orlov S Nicole | Sell | 5.7K | $127.71 |
| 2025-08-14 | Schaeffer Orlov S Nicole | Sell | 3.6K | $126.57 |
| 2025-08-13 | SHAROKY MELVIN MD | Gift | 5.0K | — |
| 2025-08-13 | SHAROKY MELVIN MD | Gift | 6.1K | — |
| 2025-08-13 | SHAROKY MELVIN MD | Gift | 15K | — |
| 2025-08-12 | SHAROKY MELVIN MD | Sell | 10K | $121.58 |
| 2025-08-04 | Lewis William | Sell | 1.9K | $110.91 |
| 2025-08-04 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-08-04 | Lewis William | Sell | 1.7K | $108.80 |
| 2025-08-04 | Flammer Martina M.D. | Sell | 8.7K | $109.50 |
| 2025-08-04 | Flammer Martina M.D. | Option exercise | 8.7K | $19.74 |
| 2025-08-04 | Lewis William | Sell | 3.2K | $109.68 |
| 2025-07-21 | Bonstein Sara | Sell | 26K | $103.03 |
| 2025-07-21 | Bonstein Sara | Option exercise | 3.4K | $26.46 |
| 2025-07-21 | Bonstein Sara | Option exercise | 11K | $28.88 |
| 2025-07-21 | Bonstein Sara | Option exercise | 16K | $29.13 |
| 2025-07-21 | Bonstein Sara | Option exercise | 17K | $34.03 |
| 2025-07-21 | Bonstein Sara | Sell | 32K | $102.38 |
| 2025-07-15 | Smith Michael Alexander | Sell | 933 | $102.51 |
| 2025-07-15 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-07-15 | Lewis William | Sell | 2.2K | $101.71 |
| 2025-07-15 | Lewis William | Sell | 4.5K | $102.66 |
| 2025-07-15 | Lewis William | Sell | 170 | $103.32 |
| 2025-07-11 | Smith Michael Alexander | Sell | 748 | $96.41 |
| 2025-07-07 | Bonstein Sara | Option exercise | 6.2K | $19.74 |
| 2025-07-07 | Bonstein Sara | Option exercise | 4.4K | $24.70 |
| 2025-07-07 | Bonstein Sara | Option exercise | 24K | $26.43 |
| 2025-07-07 | Bonstein Sara | Option exercise | 14K | $26.46 |
| 2025-07-07 | Bonstein Sara | Sell | 36K | $95.66 |
| 2025-07-07 | Bonstein Sara | Sell | 22K | $96.19 |
| 2025-07-01 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-07-01 | Lewis William | Sell | 815 | $99.61 |
| 2025-07-01 | Lewis William | Sell | 2.3K | $98.83 |
| 2025-07-01 | Lewis William | Sell | 3.7K | $97.73 |
| 2025-06-23 | Bonstein Sara | Sell | 49K | $101.71 |
| 2025-06-23 | Bonstein Sara | Sell | 8.7K | $102.15 |
| 2025-06-23 | Bonstein Sara | Option exercise | 13K | $19.74 |
| 2025-06-23 | Bonstein Sara | Option exercise | 35K | $18.95 |
| 2025-06-16 | Lewis William | Sell | 7.0K | $98.50 |
| 2025-06-16 | Lewis William | Sell | 442 | $98.51 |
| 2025-06-16 | Lewis William | Sell | 1.6K | $99.65 |
| 2025-06-16 | Lewis William | Sell | 2.3K | $100.70 |
| 2025-06-16 | Lewis William | Sell | 904 | $101.39 |
| 2025-06-16 | Lewis William | Option exercise | 130K | $10.85 |
| 2025-06-16 | Lewis William | Sell | 32K | $99.51 |
| 2025-06-16 | Lewis William | Sell | 49K | $100.54 |
| 2025-06-16 | Lewis William | Sell | 42K | $101.23 |
| 2025-06-16 | Adsett Roger | Sell | 6.5K | $98.50 |
| 2025-06-16 | Adsett Roger | Sell | 4.2K | $99.32 |
| 2025-06-11 | Schaeffer Orlov S Nicole | Sell | 18K | $92.73 |
| 2025-06-11 | Schaeffer Orlov S Nicole | Sell | 11K | $93.48 |
| 2025-06-11 | Schaeffer Orlov S Nicole | Option exercise | 70K | $13.91 |
| 2025-06-11 | Schaeffer Orlov S Nicole | Sell | 34K | $95.49 |
| 2025-06-11 | Schaeffer Orlov S Nicole | Sell | 500 | $96.02 |
| 2025-06-11 | Flammer Martina M.D. | Sell | 19K | $94.50 |
| 2025-06-11 | Flammer Martina M.D. | Option exercise | 19K | $17.07 |
| 2025-06-11 | Schaeffer Orlov S Nicole | Sell | 35K | $91.68 |
| 2025-06-10 | Bonstein Sara | Sell | 100 | $91.66 |
| 2025-06-10 | Schaeffer Orlov S Nicole | Sell | 38K | $88.64 |
| 2025-06-10 | Schaeffer Orlov S Nicole | Option exercise | 38K | $17.16 |
| 2025-06-10 | Flammer Martina M.D. | Sell | 26K | $88.64 |
| 2025-06-10 | Flammer Martina M.D. | Option exercise | 26K | $26.46 |
| 2025-06-10 | Bonstein Sara | Option exercise | 24K | $18.95 |
| 2025-06-10 | Bonstein Sara | Option exercise | 24K | $17.07 |
| 2025-06-10 | Bonstein Sara | Sell | 7.3K | $87.12 |
| 2025-06-10 | Bonstein Sara | Sell | 7.3K | $88.29 |
| 2025-06-10 | Bonstein Sara | Sell | 21K | $88.99 |
| 2025-06-10 | Bonstein Sara | Sell | 16K | $89.85 |
| 2025-06-10 | Bonstein Sara | Sell | 6.3K | $90.93 |
| 2025-06-05 | Smith Michael Alexander | Sell | 1.9K | $73.50 |
| 2025-06-04 | MCGIRR DAVID W J | Sell | 3.0K | $73.27 |
| 2025-06-03 | Bonstein Sara | Sell | 1.6K | $71.50 |
| 2025-06-03 | Smith Michael Alexander | Sell | 1.4K | $71.50 |
| 2025-06-03 | Flammer Martina M.D. | Sell | 1.7K | $71.50 |
| 2025-06-03 | Adsett Roger | Sell | 1.9K | $71.50 |
| 2025-06-03 | MCGIRR DAVID W J | Sell | 3.2K | $71.30 |
| 2025-06-03 | Schaeffer Orlov S Nicole | Sell | 1.6K | $71.50 |
| 2025-06-03 | Lewis William | Sell | 5.5K | $71.50 |
| 2025-06-02 | Lewis William | Sell | 1.0K | $70.23 |
| 2025-06-02 | Lewis William | Sell | 1.4K | $71.94 |
| 2025-06-02 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-06-02 | Lewis William | Sell | 4.4K | $71.35 |
| 2025-05-30 | Smith Michael Alexander | Sell | 20K | $70.00 |
| 2025-05-30 | Smith Michael Alexander | Sell | 6.3K | $68.56 |
| 2025-05-27 | SHAROKY MELVIN MD | Gift | 200 | — |
| 2025-05-21 | Desjardins Clarissa | Buy | 1.1K | $66.35 |
| 2025-05-20 | Lewis William | Sell | 9.5K | $66.87 |
| 2025-05-20 | Lewis William | Sell | 4.5K | $67.96 |
| 2025-05-20 | Lewis William | Sell | 7.1K | $68.49 |
| 2025-05-20 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-05-20 | Lewis William | Sell | 2.9K | $66.90 |
| 2025-05-20 | Lewis William | Sell | 2.3K | $68.13 |
| 2025-05-20 | Lewis William | Sell | 1.7K | $68.54 |
| 2025-05-20 | Desjardins Clarissa | Buy | 1.9K | $66.87 |
| 2025-05-20 | SHAROKY MELVIN MD | Gift | 100 | — |
| 2025-05-20 | SHAROKY MELVIN MD | Gift | 100 | — |
| 2025-05-20 | SHAROKY MELVIN MD | Gift | 100 | — |
| 2025-05-20 | SHAROKY MELVIN MD | Gift | 100 | — |
| 2025-05-20 | SHAROKY MELVIN MD | Gift | 400 | — |
| 2025-05-16 | Flammer Martina M.D. | Sell | 1.8K | $67.53 |
| 2025-05-15 | Schaeffer Orlov S Nicole | Grant | 5.6K | — |
| 2025-05-15 | Bonstein Sara | Grant | 6.5K | — |
| 2025-05-15 | Adsett Roger | Grant | 6.5K | — |
| 2025-05-15 | Lewis William | Grant | 22K | — |
| 2025-05-15 | Flammer Martina M.D. | Grant | 6.5K | — |
| 2025-05-15 | Flammer Martina M.D. | Sell | 9.9K | $65.47 |
| 2025-05-15 | Smith Michael Alexander | Grant | 5.6K | — |
| 2025-05-15 | Brennan David R | Grant | 5.1K | — |
| 2025-05-15 | SCHAFER CAROL | Grant | 5.1K | — |
| 2025-05-15 | Desjardins Clarissa | Grant | 5.1K | — |
| 2025-05-15 | SHAROKY MELVIN MD | Grant | 5.1K | — |
| 2025-05-15 | ANDERSON ELIZABETH M | Grant | 5.1K | — |
| 2025-05-15 | MCGIRR DAVID W J | Grant | 5.1K | — |
| 2025-05-15 | LEE LEO | Grant | 5.1K | — |
| 2025-05-14 | SHAROKY MELVIN MD | Gift | 576 | — |
| 2025-05-14 | Lewis William | Sell | 3.8K | $65.61 |
| 2025-05-14 | Smith Michael Alexander | Sell | 409 | $65.61 |
| 2025-05-14 | Schaeffer Orlov S Nicole | Sell | 1.2K | $65.61 |
| 2025-05-14 | Bonstein Sara | Sell | 1.6K | $65.61 |
| 2025-05-14 | Flammer Martina M.D. | Sell | 1.7K | $65.61 |
| 2025-05-14 | Adsett Roger | Sell | 1.9K | $65.61 |
| 2025-05-14 | SHAROKY MELVIN MD | Gift | 576 | — |
| 2025-05-13 | Smith Michael Alexander | Sell | 4.4K | $67.81 |
| 2025-05-13 | Flammer Martina M.D. | Sell | 8.4K | $67.81 |
| 2025-05-13 | Bonstein Sara | Sell | 8.9K | $67.81 |
| 2025-05-13 | Adsett Roger | Sell | 7.5K | $67.81 |
| 2025-05-13 | Lewis William | Sell | 7.7K | $67.70 |
| 2025-05-13 | Lewis William | Sell | 9.7K | $66.40 |
| 2025-05-13 | Schaeffer Orlov S Nicole | Sell | 5.0K | $67.81 |
| 2025-05-01 | Lewis William | Sell | 4.2K | $72.78 |
| 2025-05-01 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-05-01 | Lewis William | Sell | 2.6K | $72.24 |
| 2025-04-15 | Lewis William | Sell | 600 | $71.30 |
| 2025-04-15 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-04-15 | Lewis William | Sell | 3.3K | $69.62 |
| 2025-04-15 | Lewis William | Sell | 2.9K | $70.54 |
| 2025-04-01 | Lewis William | Sell | 2.2K | $74.78 |
| 2025-04-01 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-04-01 | Lewis William | Sell | 3.0K | $72.29 |
| 2025-04-01 | Lewis William | Sell | 772 | $73.44 |
| 2025-04-01 | Lewis William | Sell | 805 | $75.26 |
| 2025-03-17 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-03-17 | Lewis William | Sell | 2.0K | $76.00 |
| 2025-03-17 | Lewis William | Sell | 2.1K | $77.01 |
| 2025-03-17 | Lewis William | Option exercise | 19K | $22.76 |
| 2025-03-17 | Lewis William | Sell | 4.7K | $75.91 |
| 2025-03-17 | Lewis William | Sell | 5.9K | $76.87 |
| 2025-03-17 | Lewis William | Sell | 2.7K | $77.83 |
| 2025-03-17 | Lewis William | Sell | 8.1K | $77.79 |
| 2025-03-03 | Lewis William | Option exercise | 19K | $22.76 |
| 2025-03-03 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-03-03 | Lewis William | Sell | 2.7K | $76.23 |
| 2025-03-03 | Lewis William | Sell | 1.5K | $78.20 |
| 2025-03-03 | Lewis William | Sell | 2.2K | $78.97 |
| 2025-03-03 | Lewis William | Sell | 377 | $79.73 |
| 2025-03-03 | Lewis William | Sell | 46 | $80.90 |
| 2025-03-03 | Lewis William | Sell | 2.8K | $79.43 |
| 2025-03-03 | Lewis William | Sell | 127 | $80.90 |
| 2025-03-03 | Lewis William | Sell | 7.8K | $78.61 |
| 2025-03-03 | Lewis William | Sell | 758 | $77.75 |
| 2025-03-03 | Lewis William | Sell | 7.3K | $76.24 |
| 2025-02-25 | SHAROKY MELVIN MD | Gift | 481 | — |
| 2025-02-25 | SHAROKY MELVIN MD | Gift | 481 | — |
| 2025-02-25 | SHAROKY MELVIN MD | Gift | 1.4K | — |
| 2025-02-25 | SHAROKY MELVIN MD | Gift | 481 | — |
| 2025-02-18 | Lewis William | Sell | 6.1K | $81.07 |
| 2025-02-18 | Lewis William | Sell | 300 | $81.81 |
| 2025-02-18 | Bonstein Sara | Sell | 18K | $80.28 |
| 2025-02-18 | Bonstein Sara | Sell | 700 | $81.00 |
| 2025-02-18 | Lewis William | Option exercise | 19K | $22.76 |
| 2025-02-18 | Lewis William | Sell | 17K | $81.08 |
| 2025-02-18 | Lewis William | Sell | 1.3K | $79.95 |
| 2025-02-18 | Lewis William | Sell | 754 | $81.67 |
| 2025-02-18 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-02-18 | Lewis William | Sell | 456 | $80.00 |
| 2025-02-12 | Bonstein Sara | Sell | 5.0K | $80.00 |
| 2025-02-11 | Bonstein Sara | Sell | 13K | $80.00 |
| 2025-02-10 | Flammer Martina M.D. | Sell | 23K | $79.33 |
| 2025-02-10 | Flammer Martina M.D. | Sell | 5.1K | $78.36 |
| 2025-02-10 | Flammer Martina M.D. | Sell | 9.7K | $77.02 |
| 2025-02-10 | Adsett Roger | Sell | 26K | $79.33 |
| 2025-02-10 | Adsett Roger | Sell | 5.8K | $78.36 |
| 2025-02-10 | Adsett Roger | Sell | 11K | $77.02 |
| 2025-02-07 | Adsett Roger | Sell | 100 | $79.57 |
| 2025-02-07 | Wise John Drayton | Sell | 10 | $78.91 |
| 2025-02-07 | Flammer Martina M.D. | Sell | 60 | $79.59 |
| 2025-02-06 | Adsett Roger | Sell | 46K | $80.90 |
| 2025-02-06 | Lewis William | Sell | 79K | $80.90 |
| 2025-02-06 | Wise John Drayton | Sell | 7.9K | $80.90 |
| 2025-02-06 | Bonstein Sara | Sell | 28K | $80.90 |
| 2025-02-06 | Smith Michael Alexander | Sell | 21K | $80.90 |
| 2025-02-06 | Flammer Martina M.D. | Sell | 33K | $80.90 |
| 2025-02-06 | Schaeffer Orlov S Nicole | Sell | 24K | $80.90 |
| 2025-02-05 | Schaeffer Orlov S Nicole | Grant | 47K | — |
| 2025-02-05 | Flammer Martina M.D. | Grant | 71K | — |
| 2025-02-05 | Adsett Roger | Grant | 89K | — |
| 2025-02-05 | Wise John Drayton | Grant | 15K | — |
| 2025-02-05 | Bonstein Sara | Grant | 65K | — |
| 2025-02-05 | Lewis William | Grant | 154K | — |
| 2025-02-05 | Smith Michael Alexander | Grant | 47K | — |
| 2025-02-03 | Lewis William | Sell | 745 | $76.43 |
| 2025-02-03 | Lewis William | Option exercise | 19K | $22.76 |
| 2025-02-03 | Lewis William | Sell | 241 | $75.25 |
| 2025-02-03 | Lewis William | Sell | 1.9K | $76.35 |
| 2025-02-03 | Lewis William | Sell | 9.9K | $77.97 |
| 2025-02-03 | Lewis William | Sell | 6.8K | $78.44 |
| 2025-02-03 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-02-03 | Lewis William | Sell | 41 | $74.86 |
| 2025-02-03 | Lewis William | Sell | 3.5K | $77.95 |
| 2025-02-03 | Lewis William | Sell | 2.6K | $78.40 |
| 2025-01-30 | Schaeffer Orlov S Nicole | Option exercise | 50K | $16.16 |
| 2025-01-30 | Schaeffer Orlov S Nicole | Sell | 91K | $80.00 |
| 2025-01-30 | Schaeffer Orlov S Nicole | Option exercise | 41K | $13.67 |
| 2025-01-15 | Lewis William | Sell | 1.5K | $69.40 |
| 2025-01-15 | Lewis William | Option exercise | 19K | $22.76 |
| 2025-01-15 | Lewis William | Sell | 23K | $70.32 |
| 2025-01-15 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-01-15 | Lewis William | Sell | 2.5K | $71.05 |
| 2025-01-15 | Lewis William | Sell | 6.6K | $69.39 |
| 2025-01-15 | Lewis William | Sell | 631 | $71.01 |
| 2025-01-15 | Lewis William | Sell | 4.7K | $70.31 |
| 2025-01-14 | Adsett Roger | Sell | 1.5K | $68.72 |
| 2025-01-14 | Flammer Martina M.D. | Sell | 1.4K | $68.72 |
| 2025-01-14 | Schaeffer Orlov S Nicole | Sell | 872 | $68.72 |
| 2025-01-10 | Flammer Martina M.D. | Sell | 1.4K | $63.73 |
| 2025-01-10 | Adsett Roger | Sell | 1.3K | $63.86 |
| 2025-01-10 | Bonstein Sara | Sell | 1.1K | $63.72 |
| 2025-01-10 | Lewis William | Sell | 3.0K | $63.36 |
| 2025-01-10 | Adsett Roger | Sell | 3.6K | $63.62 |
| 2025-01-10 | Wise John Drayton | Sell | 287 | $65.40 |
| 2025-01-10 | Schaeffer Orlov S Nicole | Sell | 965 | $63.87 |
| 2025-01-10 | Schaeffer Orlov S Nicole | Sell | 3.1K | $63.62 |
| 2025-01-10 | Smith Michael Alexander | Sell | 319 | $63.38 |
| 2025-01-10 | Flammer Martina M.D. | Sell | 4.8K | $63.62 |
| 2025-01-08 | Adsett Roger | Grant | 6.7K | — |
| 2025-01-08 | Flammer Martina M.D. | Sell | 1.7K | $66.16 |
| 2025-01-08 | Flammer Martina M.D. | Grant | 6.7K | — |
| 2025-01-08 | Bonstein Sara | Sell | 1.5K | $66.05 |
| 2025-01-08 | Bonstein Sara | Grant | 6.7K | — |
| 2025-01-08 | Schaeffer Orlov S Nicole | Sell | 1.2K | $65.84 |
| 2025-01-08 | Schaeffer Orlov S Nicole | Grant | 5.7K | — |
| 2025-01-08 | Wise John Drayton | Sell | 392 | $66.21 |
| 2025-01-08 | Wise John Drayton | Grant | 6.7K | — |
| 2025-01-08 | Lewis William | Sell | 4.0K | $65.96 |
| 2025-01-08 | Lewis William | Grant | 23K | — |
| 2025-01-08 | Smith Michael Alexander | Sell | 1.1K | $66.21 |
| 2025-01-08 | Smith Michael Alexander | Grant | 5.7K | — |
| 2025-01-08 | Adsett Roger | Sell | 1.9K | $66.10 |
| 2025-01-07 | Adsett Roger | Sell | 2.4K | $65.95 |
| 2025-01-07 | Smith Michael Alexander | Sell | 2.3K | $65.98 |
| 2025-01-07 | Lewis William | Sell | 8.2K | $66.02 |
| 2025-01-07 | Wise John Drayton | Option exercise | 10K | $16.07 |
| 2025-01-07 | Schaeffer Orlov S Nicole | Sell | 2.6K | $65.88 |
| 2025-01-07 | Bonstein Sara | Sell | 3.5K | $65.70 |
| 2025-01-07 | Flammer Martina M.D. | Sell | 3.3K | $65.91 |
| 2025-01-07 | Wise John Drayton | Sell | 2.9K | $65.87 |
| 2025-01-07 | Wise John Drayton | Sell | 10K | $65.98 |
| 2025-01-02 | Lewis William | Option exercise | 19K | $22.76 |
| 2025-01-02 | Lewis William | Sell | 19K | $69.84 |
| 2025-01-02 | Lewis William | Option exercise | 6.8K | $10.85 |
| 2025-01-02 | Lewis William | Sell | 6.8K | $69.86 |
All non-derivative Form 4 activity (SEC), newest first.
Notable events (8-K)
| Date | Items | |
|---|---|---|
| 2026-05-15 | Shareholder vote | filing ↗ |
| 2026-05-07 | ResultsExhibits | filing ↗ |
| 2026-04-07 | Reg FDOtherExhibits | filing ↗ |
| 2026-03-23 | Reg FDOtherExhibits | filing ↗ |
| 2026-02-19 | ResultsExec/director changeExhibits | filing ↗ |
| 2026-01-09 | Reg FDExhibits | filing ↗ |
| 2025-12-17 | Reg FDOtherExhibits | filing ↗ |
| 2025-11-18 | Reg FDOtherExhibits | filing ↗ |
Recent filings
| Form | Filed | Period | Accession |
|---|---|---|---|
| 8-K | 2026-05-15 | 2026-05-13 | 0001140361-26-021648 ↗ |
| 8-K | 2026-05-07 | 2026-05-07 | 0001140361-26-019430 ↗ |
| 10-Q | 2026-05-07 | 2026-03-31 | 0001104506-26-000032 ↗ |
| 8-K | 2026-04-07 | 2026-04-07 | 0001140361-26-013659 ↗ |
| 8-K | 2026-03-23 | 2026-03-23 | 0001140361-26-010651 ↗ |
| 8-K | 2026-02-19 | 2026-02-17 | 0001140361-26-006116 ↗ |
| 10-K | 2026-02-19 | 2025-12-31 | 0001104506-26-000009 ↗ |
| 8-K | 2026-01-09 | 2026-01-09 | 0001140361-26-000778 ↗ |
| 8-K | 2025-12-17 | 2025-12-17 | 0001140361-25-045836 ↗ |
| 8-K | 2025-11-18 | 2025-11-18 | 0001140361-25-042598 ↗ |
| 8-K | 2025-10-30 | 2025-10-30 | 0001140361-25-039789 ↗ |
| 10-Q | 2025-10-30 | 2025-09-30 | 0001104506-25-000053 ↗ |