MACROGENICS INC
MGNX · Pharmaceutical Preparations · 63.6M shares · +7%/yr ↑ dilution · EDGAR filings ↗
Reference price $1.49 · est. market cap ~$95M — last insider purchase, 2025-08-20 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)
Grade
D46Clinical/early-stage biotech — antibody biotech, losses but funded.
Strengths
- Liquidity — current ratio 5.1 (59th)
Risks
- Pre-revenue, deep losses — per metrics
- Pre-revenue/clinical-stage — history of losses & need for capital per risk factors
- Binary clinical & funding risk — per 10-K
Notable findings
- Net lossNet loss (net margin -49.9%)
- Cash burnNegative free cash flow (-83.0M)
- Fund exitedNotable fund(s) exited this quarter: VANGUARD GROUP INC
- Revenue declineRevenue -49.6% YoY
- Notable holderHeld by 5 notable fund(s): RENAISSANCE TECHNOLOGIES LLC, CITADEL ADVISORS LLC, STATE STREET CORP +2 more (as of 2026-03-31)
Quarterly revenue
Last 4 quarters · from SEC filings.
Key metrics
Gross margin
100.0%
Operating margin
-48.7%
Net margin
-49.9%
Return on equity
-134.2%
Return on assets
-29.1%
Revenue growth (QoQ)
-49.6%
Current ratio
5.1×
Free cash flow
-$83M
EBITDA
-$66M
Tangible book value
$56M
Cash & investments
$57M
Cash runway
3q
Stock comp / revenue
9.6%
Insider transactions · last 18 months
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| 2026-05-18 | O'Brien Federica F. | Option exercise | 3.8K | — |
| 2026-05-18 | SIEGEL JAY PHILIP | Option exercise | 3.8K | — |
| 2026-05-18 | Ferrante Karen Jean | Option exercise | 3.8K | — |
| 2026-05-18 | Jackson Scott Thomas | Option exercise | 3.8K | — |
| 2026-05-18 | Chhabra Meenu | Option exercise | 3.8K | — |
| 2026-05-18 | Liu Margaret | Option exercise | 3.8K | — |
| 2026-05-18 | HEIDEN WILLIAM K | Option exercise | 3.8K | — |
| 2026-05-18 | HURWITZ EDWARD | Option exercise | 3.8K | — |
| 2026-05-18 | STUMP DAVID C | Option exercise | 3.8K | — |
| 2026-02-15 | Peters Jeffrey Stuart | Tax withheld | 5.1K | $1.71 |
| 2026-02-15 | Spitznagel Thomas | Option exercise | 13K | — |
| 2026-02-15 | Spitznagel Thomas | Tax withheld | 5.5K | $1.71 |
| 2026-02-15 | Bonvini Ezio | Option exercise | 17K | — |
| 2026-02-15 | Bonvini Ezio | Tax withheld | 6.4K | $1.71 |
| 2026-02-15 | Risser Eric Blasius | Option exercise | 17K | — |
| 2026-02-15 | Risser Eric Blasius | Tax withheld | 6.4K | $1.71 |
| 2026-02-15 | Smith Beth Ann | Option exercise | 1.1K | — |
| 2026-02-15 | Smith Beth Ann | Tax withheld | 423 | $1.71 |
| 2026-02-15 | Koenig Scott | Option exercise | 21K | — |
| 2026-02-15 | Karrels James | Option exercise | 15K | — |
| 2026-02-15 | Karrels James | Tax withheld | 5.8K | $1.71 |
| 2026-02-15 | Peters Jeffrey Stuart | Option exercise | 13K | — |
| 2026-02-08 | Peters Jeffrey Stuart | Option exercise | 9.0K | — |
| 2026-02-08 | Karrels James | Option exercise | 10.0K | — |
| 2026-02-08 | Karrels James | Tax withheld | 3.9K | $1.81 |
| 2026-02-08 | Spitznagel Thomas | Tax withheld | 3.2K | $1.81 |
| 2026-02-08 | Peters Jeffrey Stuart | Tax withheld | 3.5K | $1.81 |
| 2026-02-08 | Smith Beth Ann | Option exercise | 1.6K | — |
| 2026-02-08 | Smith Beth Ann | Tax withheld | 612 | $1.81 |
| 2026-02-08 | Spitznagel Thomas | Option exercise | 9.0K | — |
| 2026-02-08 | Bonvini Ezio | Option exercise | 11K | — |
| 2026-02-08 | Bonvini Ezio | Tax withheld | 4.3K | $1.81 |
| 2026-02-08 | Risser Eric Blasius | Option exercise | 11K | — |
| 2026-02-08 | Risser Eric Blasius | Tax withheld | 4.3K | $1.81 |
| 2026-02-08 | Koenig Scott | Option exercise | 16K | — |
| 2026-02-07 | Karrels James | Tax withheld | 2.4K | $1.81 |
| 2026-02-07 | Smith Beth Ann | Option exercise | 2.6K | — |
| 2026-02-07 | Smith Beth Ann | Tax withheld | 1.0K | $1.81 |
| 2026-02-07 | Peters Jeffrey Stuart | Option exercise | 6.0K | — |
| 2026-02-07 | Peters Jeffrey Stuart | Tax withheld | 2.3K | $1.81 |
| 2026-02-07 | Spitznagel Thomas | Option exercise | 6.0K | — |
| 2026-02-07 | Spitznagel Thomas | Tax withheld | 2.5K | $1.81 |
| 2026-02-07 | Bonvini Ezio | Option exercise | 7.0K | — |
| 2026-02-07 | Bonvini Ezio | Tax withheld | 2.7K | $1.81 |
| 2026-02-07 | Risser Eric Blasius | Option exercise | 6.7K | — |
| 2026-02-07 | Risser Eric Blasius | Tax withheld | 2.6K | $1.81 |
| 2026-02-07 | Karrels James | Option exercise | 6.3K | — |
| 2025-08-20 | HEIDEN WILLIAM K | Buy | 50K | $1.49 |
| 2025-08-19 | HEIDEN WILLIAM K | Buy | 50K | $1.52 |
| 2025-08-13 | Koenig Scott | Option exercise | 21K | — |
| 2025-08-13 | Koenig Scott | Option exercise | 32K | — |
| 2025-05-20 | HEIDEN WILLIAM K | Option exercise | 6.5K | — |
| 2025-05-20 | STUMP DAVID C | Option exercise | 6.5K | — |
| 2025-05-20 | Ferrante Karen Jean | Option exercise | 6.5K | — |
| 2025-05-20 | Liu Margaret | Option exercise | 6.5K | — |
| 2025-05-20 | HURWITZ EDWARD | Option exercise | 6.5K | — |
| 2025-05-20 | Chhabra Meenu | Option exercise | 6.5K | — |
| 2025-05-20 | SIEGEL JAY PHILIP | Option exercise | 6.5K | — |
| 2025-05-20 | Jackson Scott Thomas | Option exercise | 6.5K | — |
| 2025-05-20 | O'Brien Federica F. | Option exercise | 6.5K | — |
| 2025-02-15 | Eck Stephen L. | Option exercise | 17K | — |
| 2025-02-15 | Eck Stephen L. | Tax withheld | 4.9K | $2.56 |
| 2025-02-15 | Bonvini Ezio | Option exercise | 17K | — |
| 2025-02-15 | Karrels James | Option exercise | 15K | — |
| 2025-02-15 | Karrels James | Tax withheld | 5.8K | $2.56 |
| 2025-02-15 | Koenig Scott | Option exercise | 42K | — |
| 2025-02-15 | Peters Jeffrey Stuart | Option exercise | 13K | — |
| 2025-02-15 | Peters Jeffrey Stuart | Tax withheld | 5.1K | $2.56 |
| 2025-02-15 | Risser Eric Blasius | Option exercise | 17K | — |
| 2025-02-15 | Risser Eric Blasius | Tax withheld | 6.4K | $2.56 |
| 2025-02-15 | Smith Beth Ann | Option exercise | 1.1K | — |
| 2025-02-15 | Smith Beth Ann | Sell | 423 | $2.56 |
| 2025-02-15 | Spitznagel Thomas | Option exercise | 13K | — |
| 2025-02-15 | Spitznagel Thomas | Tax withheld | 5.5K | $2.56 |
| 2025-02-08 | Eck Stephen L. | Option exercise | 11K | — |
| 2025-02-08 | Eck Stephen L. | Tax withheld | 3.3K | $2.60 |
| 2025-02-08 | Bonvini Ezio | Option exercise | 11K | — |
| 2025-02-08 | Bonvini Ezio | Tax withheld | 4.3K | $2.60 |
| 2025-02-08 | Risser Eric Blasius | Option exercise | 11K | — |
| 2025-02-08 | Risser Eric Blasius | Tax withheld | 4.3K | $2.60 |
| 2025-02-08 | Karrels James | Option exercise | 10K | — |
| 2025-02-08 | Karrels James | Tax withheld | 3.9K | $2.60 |
| 2025-02-08 | Smith Beth Ann | Option exercise | 1.6K | — |
| 2025-02-08 | Smith Beth Ann | Tax withheld | 612 | $2.60 |
| 2025-02-08 | Koenig Scott | Grant | 32K | — |
| 2025-02-08 | Spitznagel Thomas | Option exercise | 9.0K | — |
| 2025-02-08 | Spitznagel Thomas | Tax withheld | 3.7K | $2.60 |
| 2025-02-08 | Peters Jeffrey Stuart | Option exercise | 9.0K | — |
| 2025-02-08 | Peters Jeffrey Stuart | Tax withheld | 3.5K | $2.60 |
All non-derivative Form 4 activity (SEC), newest first.
Supply chain
Customers (2)
Suppliers (2)
- Lonza
- Synaffix B.V.
Named in the 10-K; linked when we track them.
Notable events (8-K)
Recent filings
| Form | Filed | Period | Accession |
|---|---|---|---|
| 8-K | 2026-05-20 | 2026-05-19 | 0001125345-26-000042 ↗ |
| 10-Q | 2026-05-13 | 2026-03-31 | 0001125345-26-000038 ↗ |
| 8-K | 2026-05-13 | 2026-05-13 | 0001125345-26-000040 ↗ |
| 8-K | 2026-05-12 | 2026-05-11 | 0001125345-26-000035 ↗ |
| 8-K | 2026-05-04 | 2026-05-01 | 0001125345-26-000032 ↗ |
| 8-K | 2026-04-08 | 2026-04-08 | 0001125345-26-000026 ↗ |
| 8-K | 2026-03-09 | 2026-03-09 | 0001125345-26-000018 ↗ |
| 10-K | 2026-03-09 | 2025-12-31 | 0001125345-26-000017 ↗ |
| 8-K | 2026-03-02 | 2026-03-02 | 0001125345-26-000011 ↗ |
| 8-K | 2026-02-24 | 2026-02-23 | 0001125345-26-000009 ↗ |
| 8-K | 2025-11-20 | 2025-11-14 | 0001125345-25-000111 ↗ |
| 8-K | 2025-11-12 | 2025-11-12 | 0001125345-25-000109 ↗ |