Jazz Pharmaceuticals plc

JAZZ · Pharmaceutical Preparations · 62.7M shares · +6%/yr ↑ dilution · EDGAR filings ↗

Net buyback after stock comp: $43M (gross $270M, SBC $227M)

Reference price $230.55 · est. market cap ~$14.5B — last insider sale, 2026-06-15 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)

Grade

B72

Specialty pharma with strong free cash flow, but a charge-driven GAAP loss and leverage.

Strengths

Strong free cash flow — FCF $1.3B (97th), FCF margin 30%
Diversified marketed portfolio (Xywav/Epidiolex/Rylaze) — per 10-K

Risks

GAAP loss (acquisition/IPR&D charges) — operating margin -10%, net income -164%
Leverage — D/E 1.0 (81st)
Oxybate-franchise/patent dependence — per 10-K

Notable findings

Exec changeRecent 8-K item 5.02 8-K ↗
Net lossNet loss (net margin -8.3%)
Trial resultPositive trial readout — primary endpoint met (8-K) 8-K ↗
Revenue declineRevenue -10.8% YoY
Insider sellingInsider selling — 30 open-market sale(s) by 9 insider(s) (cluster of 9 insiders, ~$22M, last 6mo) Form 4 ↗

Quarterly revenue

2025-06-30 · $1.0B2025-09-30 · $1.1B2025-12-31 · $1.2B2026-03-31 · $1.1B

Last 4 quarters · from SEC filings.

Key metrics

Operating margin

-10.1%

Net margin

-8.3%

Return on equity

-8.2%

Return on assets

-3.1%

ROIC

-3.9%

Revenue growth (QoQ)

-10.8%

Net-income growth

-163.6%

Debt / equity

1.0×

Current ratio

1.9×

Free cash flow

$1.3B

EBITDA

-$389M

Tangible book value

-$1.9B

Cash & investments

$1.4B

Stock comp / revenue

6.8%

Insider transactions · last 18 months

Date	Insider	Type	Shares	Price
2026-06-15	Smith Mark Douglas	Sell	1.2K	$230.55
2026-06-10	Patil Neena M	Sell	1.2K	$231.83
2026-06-03	GALA RENEE D	Gift	600	—
2026-06-01	COZADD BRUCE C	Sell	6.0K	$235.12
2026-05-28	Pearce Samantha	Sell	6.9K	$235.41
2026-05-28	Patil Neena M	Sell	1.2K	$236.97
2026-05-28	Mulligan Seamus	Option exercise	3.4K	$138.08
2026-05-28	Pearce Samantha	Option exercise	6.9K	$109.45
2026-05-22	Winningham Rick E	Option exercise	3.4K	$138.08
2026-05-22	Winningham Rick E	Sell	2.7K	$241.57
2026-05-22	McSharry Heather Ann	Sell	2.0K	$241.00
2026-05-01	COZADD BRUCE C	Sell	6.0K	$203.33
2026-04-01	COZADD BRUCE C	Sell	3.7K	$190.22
2026-04-01	COZADD BRUCE C	Sell	24	$191.74
2026-04-01	COZADD BRUCE C	Sell	2.3K	$190.94
2026-03-09	Carr Patricia	Sell	1.3K	$182.94
2026-03-05	Patil Neena M	Tax withheld	5.0K	$188.69
2026-03-05	Iannone Robert	Tax withheld	6.2K	$188.69
2026-03-05	GALA RENEE D	Tax withheld	7.1K	$188.69
2026-03-05	COZADD BRUCE C	Tax withheld	15K	$188.69
2026-03-05	Carr Patricia	Tax withheld	1.4K	$186.77
2026-03-05	Johnson Philip L	Tax withheld	2.6K	$188.69
2026-03-05	Henderson Mary Elizabeth	Tax withheld	1.4K	$186.75
2026-03-05	Pearce Samantha	Tax withheld	2.5K	$188.69
2026-03-03	COZADD BRUCE C	Sell	2.6K	$186.73
2026-03-03	COZADD BRUCE C	Sell	233	$187.84
2026-03-03	COZADD BRUCE C	Sell	3.2K	$186.09
2026-02-27	RIEDEL NORBERT G	Sell	3.4K	$192.00
2026-02-27	Carr Patricia	Sell	1.1K	$190.91
2026-02-27	RIEDEL NORBERT G	Option exercise	3.4K	$138.08
2026-02-26	GALA RENEE D	Grant	44K	—
2026-02-26	Johnson Philip L	Grant	12K	—
2026-02-26	Henderson Mary Elizabeth	Grant	4.4K	—
2026-02-26	Henderson Mary Elizabeth	Sell	5.3K	$194.49
2026-02-26	Pearce Samantha	Grant	9.8K	—
2026-02-26	Carr Patricia	Grant	2.2K	—
2026-02-26	Carr Patricia	Sell	1.3K	$194.11
2026-02-26	Patil Neena M	Option exercise	20K	$113.10
2026-02-26	Patil Neena M	Sell	17K	$192.53
2026-02-26	Patil Neena M	Option exercise	875	$113.10
2026-02-26	Patil Neena M	Sell	875	$192.07
2026-02-26	Patil Neena M	Option exercise	27K	$137.12
2026-02-26	Patil Neena M	Sell	16K	$190.28
2026-02-26	Patil Neena M	Option exercise	2.9K	$137.12
2026-02-26	Patil Neena M	Sell	2.9K	$189.81
2026-02-26	Patil Neena M	Grant	10K	—
2026-02-26	Patil Neena M	Sell	12K	$191.65
2026-02-26	Patil Neena M	Sell	3.5K	$193.58
2026-02-26	Patil Neena M	Sell	1.1K	$190.00
2026-02-26	Patil Neena M	Sell	549	$190.80
2026-02-26	Patil Neena M	Sell	1.8K	$191.88
2026-02-26	Patil Neena M	Sell	1.0K	$192.79
2026-02-26	Patil Neena M	Sell	197	$193.60
2026-02-26	Iannone Robert	Grant	15K	—
2026-02-26	LOVE TED W	Grant	1.5K	—
2026-01-16	Henderson Mary Elizabeth	Grant	10K	—
2026-01-16	Pearce Samantha	Grant	3.6K	—
2026-01-16	Pearce Samantha	Tax withheld	1.6K	$171.16
2026-01-16	Carr Patricia	Grant	2.4K	—
2026-01-16	Patil Neena M	Grant	8.9K	—
2026-01-16	Patil Neena M	Disposition	3.3K	$171.16
2026-01-16	Iannone Robert	Grant	12K	—
2026-01-16	Iannone Robert	Tax withheld	4.1K	$171.16
2026-01-16	GALA RENEE D	Grant	13K	—
2026-01-16	GALA RENEE D	Tax withheld	5.4K	$171.16
2026-01-16	COZADD BRUCE C	Grant	36K	—
2026-01-16	COZADD BRUCE C	Tax withheld	17K	$171.16
2025-12-09	Henderson Mary Elizabeth	Sell	2.2K	$169.51
2025-12-05	Carr Patricia	Sell	160	$171.11
2025-12-05	Carr Patricia	Option exercise	4.5K	$140.67
2025-12-05	Carr Patricia	Sell	4.5K	$171.20
2025-12-05	GALA RENEE D	Tax withheld	80	$166.91
2025-12-02	O'Keefe Kenneth W	Tax withheld	603	$173.07
2025-11-26	COZADD BRUCE C	Option exercise	77K	$123.36
2025-11-26	COZADD BRUCE C	Sell	38K	$177.27
2025-11-26	COZADD BRUCE C	Sell	30K	$178.06
2025-11-26	COZADD BRUCE C	Sell	8.4K	$179.23
2025-11-26	COZADD BRUCE C	Sell	507	$179.79
2025-11-26	COZADD BRUCE C	Option exercise	811	$123.36
2025-11-20	McSharry Heather Ann	Sell	3.4K	$177.78
2025-11-20	COZADD BRUCE C	Grant	2.5K	—
2025-11-20	McSharry Heather Ann	Option exercise	3.4K	$138.08
2025-11-19	Henderson Mary Elizabeth	Disposition	1.3K	$180.40
2025-11-18	COZADD BRUCE C	Sell	717	$182.60
2025-11-18	Carr Patricia	Sell	69	$181.66
2025-11-18	Carr Patricia	Option exercise	5.2K	$136.18
2025-11-18	Carr Patricia	Sell	5.2K	$182.07
2025-11-18	Winningham Rick E	Sell	5.5K	$180.86
2025-11-18	COZADD BRUCE C	Sell	3.4K	$180.09
2025-11-18	COZADD BRUCE C	Sell	8.4K	$180.88
2025-11-18	COZADD BRUCE C	Sell	5.5K	$181.81
2025-11-17	Iannone Robert	Sell	7.2K	$168.26
2025-10-03	COZADD BRUCE C	Sell	3.5K	$140.00
2025-10-01	COZADD BRUCE C	Sell	2.0K	$131.78
2025-09-14	COZADD BRUCE C	Tax withheld	16K	$126.16
2025-09-02	COZADD BRUCE C	Sell	3.0K	$127.23
2025-09-02	COZADD BRUCE C	Sell	3.0K	$130.00
2025-08-18	ENRIGHT PATRICK G	Other	5.0K	—
2025-08-08	Kennedy Patrick	Tax withheld	2.0K	$111.25
2025-08-08	O'Keefe Kenneth W	Tax withheld	1.8K	$111.25
2025-08-08	Cook Jennifer E.	Tax withheld	1.8K	$111.25
2025-08-08	ENRIGHT PATRICK G	Tax withheld	1.8K	$111.25
2025-08-08	Hamill Laura	Tax withheld	1.8K	$111.25
2025-08-08	McSharry Heather Ann	Tax withheld	2.0K	$111.25
2025-08-08	ORiordan Anne	Tax withheld	1.8K	$111.25
2025-08-08	RIEDEL NORBERT G	Tax withheld	1.8K	$111.25
2025-08-08	Smith Mark Douglas	Tax withheld	1.8K	$111.25
2025-08-08	Winningham Rick E	Tax withheld	1.8K	$111.25
2025-08-07	McSharry Heather Ann	Grant	3.5K	—
2025-08-07	ORiordan Anne	Grant	3.5K	—
2025-08-07	RIEDEL NORBERT G	Grant	3.5K	—
2025-08-07	Smith Mark Douglas	Grant	3.5K	—
2025-08-07	Winningham Rick E	Grant	3.5K	—
2025-08-07	Mulligan Seamus	Grant	3.5K	—
2025-08-07	GALA RENEE D	Grant	19K	—
2025-08-07	Cook Jennifer E.	Grant	3.5K	—
2025-08-07	ENRIGHT PATRICK G	Grant	3.5K	—
2025-08-07	Hamill Laura	Grant	3.5K	—
2025-08-07	Kennedy Patrick	Grant	3.5K	—
2025-08-07	O'Keefe Kenneth W	Grant	3.5K	—
2025-08-05	Pearce Samantha	Tax withheld	577	$116.10
2025-08-01	COZADD BRUCE C	Sell	1.0K	$113.21
2025-07-01	COZADD BRUCE C	Sell	500	$105.26
2025-07-01	COZADD BRUCE C	Sell	500	$110.00
2025-06-03	COZADD BRUCE C	Sell	500	$110.00
2025-06-02	COZADD BRUCE C	Sell	500	$107.90
2025-05-12	Mulligan Seamus	Buy	1.6K	$103.00
2025-05-09	Mulligan Seamus	Buy	19K	$98.91
2025-05-09	Mulligan Seamus	Buy	100	$99.71
2025-05-09	Mulligan Seamus	Buy	81K	$98.10
2025-05-02	COZADD BRUCE C	Sell	500	$120.00
2025-05-01	COZADD BRUCE C	Sell	1.0K	$116.35
2025-04-01	COZADD BRUCE C	Sell	1.5K	$123.75
2025-03-10	Carr Patricia	Sell	1.1K	$137.81
2025-03-10	Iannone Robert	Sell	2.4K	$138.41
2025-03-07	Iannone Robert	Sell	1.5K	$140.00
2025-03-07	Carr Patricia	Disposition	1.3K	$138.23
2025-03-07	Iannone Robert	Sell	5.5K	$138.21
2025-03-07	Henderson Mary Elizabeth	Disposition	698	$138.23
2025-03-05	Patil Neena M	Disposition	4.1K	$138.95
2025-03-05	COZADD BRUCE C	Disposition	22K	$138.95
2025-03-05	GALA RENEE D	Disposition	5.7K	$138.95
2025-03-05	Johnson Philip L	Disposition	1.1K	$138.95
2025-03-05	Iannone Robert	Disposition	5.2K	$138.95
2025-03-05	Pearce Samantha	Disposition	1.9K	$138.95
2025-03-03	COZADD BRUCE C	Sell	6.5K	$144.25
2025-02-28	Carr Patricia	Sell	773	$143.29
2025-02-27	Carr Patricia	Sell	4.5K	$144.42
2025-02-27	Carr Patricia	Option exercise	313	$123.36
2025-02-27	Carr Patricia	Sell	313	$144.42
2025-02-27	Carr Patricia	Disposition	371	$142.43
2025-02-27	Carr Patricia	Disposition	497	$142.43
2025-02-27	Carr Patricia	Grant	2.9K	—
2025-02-27	Patil Neena M	Grant	13K	—
2025-02-27	Patil Neena M	Grant	5.8K	—
2025-02-27	COZADD BRUCE C	Grant	31K	—
2025-02-27	Patil Neena M	Sell	3.8K	$144.87
2025-02-27	Iannone Robert	Grant	18K	—
2025-02-27	Iannone Robert	Grant	8.9K	—
2025-02-27	Henderson Mary Elizabeth	Grant	5.4K	—
2025-02-27	Henderson Mary Elizabeth	Grant	3.9K	—
2025-02-27	Pearce Samantha	Grant	12K	—
2025-02-27	Pearce Samantha	Grant	5.8K	—
2025-02-27	GALA RENEE D	Grant	23K	—
2025-02-27	GALA RENEE D	Grant	12K	—
2025-02-27	Johnson Philip L	Grant	15K	—
2025-02-27	Johnson Philip L	Grant	7.7K	—
2025-02-27	Carr Patricia	Option exercise	4.5K	$113.10
2025-02-03	COZADD BRUCE C	Sell	1.5K	$122.31
2025-01-17	Iannone Robert	Grant	7.5K	—
2025-01-17	Iannone Robert	Tax withheld	2.2K	$122.62
2025-01-17	COZADD BRUCE C	Grant	30K	—
2025-01-17	COZADD BRUCE C	Tax withheld	14K	$122.62
2025-01-17	GALA RENEE D	Grant	7.7K	—
2025-01-17	GALA RENEE D	Tax withheld	3.3K	$122.62
2025-01-17	Carr Patricia	Grant	1.6K	—
2025-01-17	Patil Neena M	Grant	5.9K	—
2025-01-17	Patil Neena M	Tax withheld	1.9K	$122.62
2025-01-17	Pearce Samantha	Grant	2.5K	—
2025-01-17	Pearce Samantha	Tax withheld	1.4K	$122.62
2025-01-02	COZADD BRUCE C	Sell	1.5K	$123.43

All non-derivative Form 4 activity (SEC), newest first.

Clinical trials

Trial	Title	Phase	Status	Primary completion
NCT02769780 ↗	A Web-based Observational Study of Patient-reported Outcomes in Adults With Narcolepsy Narcolepsy	—	Completed	2021-08-09

Source: ClinicalTrials.gov (U.S. NIH) · active studies first.

Supply chain

Customers (0)

Suppliers (3)

Named in the 10-K; linked when we track them.

Notable events (8-K)

Date	Items
2026-05-29	Exec/director change	filing ↗
2026-05-05	ResultsExhibits	filing ↗
2026-02-24	ResultsExhibits	filing ↗
2026-01-12	ResultsExhibits	filing ↗
2025-11-17	OtherExhibits	filing ↗
2025-11-05	ResultsExhibits	filing ↗
2025-10-28	Exec/director change	filing ↗
2025-10-22	Other	filing ↗

Recent filings

Form	Filed	Period	Accession
8-K	2026-05-29	2026-05-25	0001628280-26-039147 ↗
8-K	2026-05-05	2026-05-05	0001232524-26-000024 ↗
10-Q	2026-05-05	2026-03-31	0001232524-26-000025 ↗
10-K/A	2026-04-24	2025-12-31	0001628280-26-027205 ↗
8-K	2026-02-24	2026-02-24	0001232524-26-000012 ↗
10-K	2026-02-24	2025-12-31	0001232524-26-000013 ↗
8-K	2026-01-12	2026-01-12	0001193125-26-009899 ↗
8-K	2025-11-17	2025-11-17	0001193125-25-283887 ↗
10-Q	2025-11-05	2025-09-30	0001232524-25-000074 ↗
8-K	2025-11-05	2025-11-05	0001232524-25-000073 ↗
8-K	2025-10-28	2025-10-23	0001628280-25-046763 ↗
8-K	2025-10-22	2025-10-21	0001193125-25-245815 ↗