ProMIS Neurosciences Inc.
PMN · Pharmaceutical Preparations · 9.0M shares · -43%/yr ↓ buyback · EDGAR filings ↗
Reference price $11.33 · est. market cap ~$102M — last insider purchase, 2026-04-22 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)
Grade
F32Dormant/near-insolvent micro-cap — near-insolvent liquidity and deep losses.
Strengths
- n/a — no durable positives
Risks
- Near-insolvent/negligible operations — per metrics
- Going-concern fragility — per 10-K
- Shell-like financials — per 10-K
Notable findings
- Exec changeRecent 8-K item 5.02 8-K ↗
- Weak liquidityCurrent ratio 0.88 (<1)
- Insider buyingInsider buying — 7 open-market buy(s) by 4 insider(s) (cluster of 4 insiders, ~$9M, last 6mo) Form 4 ↗
- Buying back stockNet buyback — share count -43%/yr over 3y
- Trial resultTrial topline data reported — see 8-K for outcome 8-K ↗
Key metrics
Return on equity
3155.8%
Return on assets
-432.6%
Current ratio
0.9×
Tangible book value
-$1M
Cash & investments
$6M
Insider transactions · last 18 months
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| 2026-04-22 | Kirwin Patrick D. | Buy | 4.0K | $11.33 |
| 2026-03-05 | Williams Eugene | Buy | 2.0K | $24.40 |
| 2026-03-04 | Williams Eugene | Buy | 2.0K | $24.00 |
| 2026-03-03 | Williams Eugene | Buy | 1.0K | $21.89 |
| 2026-03-02 | Williams Eugene | Buy | 1.0K | $22.53 |
| 2026-02-19 | Kaplan Johanne | Buy | 1.6K | $15.35 |
| 2026-02-03 | ABG Management Ltd. | Buy | 701K | $12.13 |
| 2026-02-03 | Cashman Neil | Grant | 4.1K | $12.13 |
| 2026-02-03 | Kaplan Johanne | Grant | 2.1K | $12.13 |
| 2026-02-03 | Warma Neil K | Grant | 6.2K | $12.13 |
| 2026-02-03 | Milbury Max A. | Grant | 6.6K | $12.13 |
| 2026-02-03 | Kirwin Patrick D. | Grant | 3.0K | $12.13 |
| 2025-10-03 | Milbury Max A. | Buy | 30K | $0.49 |
| 2025-07-25 | Jeremy M. Sclar 2012 Irrevocable Family Trust | Option exercise | 698K | — |
| 2025-07-25 | Jeremy M. Sclar 2012 Irrevocable Family Trust | Option exercise | 698K | — |
| 2025-07-25 | Jeremy M. Sclar 2012 Irrevocable Family Trust | Option exercise | 698K | — |
| 2025-07-25 | Sclar Jeremy M. | Option exercise | 698K | — |
| 2025-07-25 | Sclar Jeremy M. | Option exercise | 698K | — |
| 2025-07-25 | Sclar Jeremy M. | Option exercise | 698K | — |
| 2025-07-25 | Title 19 Promis | Option exercise | 120K | — |
| 2025-07-25 | Title 19 Promis | Option exercise | 120K | — |
| 2025-07-25 | Title 19 Promis | Option exercise | 120K | — |
| 2025-07-25 | GORDON MICHAEL S | Option exercise | 120K | — |
| 2025-07-25 | GORDON MICHAEL S | Option exercise | 120K | — |
| 2025-07-25 | GORDON MICHAEL S | Option exercise | 120K | — |
| 2025-06-30 | GORDON MICHAEL S | Sell | 93K | — |
| 2025-03-13 | GORDON MICHAEL S | Other | 48K | — |
| 2025-02-10 | Cashman Neil | Buy | 15K | $0.97 |
All non-derivative Form 4 activity (SEC), newest first.
Clinical trials
| Trial | Title | Phase | Status | Primary completion |
|---|---|---|---|---|
| NCT06750432 ↗ | PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD) Alzheimer Disease, Early Onset | PHASE1 | Active Not Recruiting | 2026-12-01 |
| NCT06105528 ↗ | A Phase 1a Study of PMN310 In Healthy Volunteers Healthy Participants | PHASE1 | Completed | 2024-07-31 |
Source: ClinicalTrials.gov (U.S. NIH) · active studies first.
Notable events (8-K)
| Date | Items | |
|---|---|---|
| 2026-05-20 | Exec/director changeShareholder voteExhibits | filing ↗ |
| 2026-05-12 | ResultsExhibits | filing ↗ |
| 2026-03-25 | ResultsExhibits | filing ↗ |
| 2026-01-30 | Material agreement3.02OtherExhibits | filing ↗ |
| 2025-12-16 | Other | filing ↗ |
| 2025-11-24 | 5.03OtherExhibits | filing ↗ |
| 2025-11-19 | Shareholder vote | filing ↗ |
| 2025-11-12 | ResultsExhibits | filing ↗ |
Recent filings
| Form | Filed | Period | Accession |
|---|---|---|---|
| 8-K | 2026-05-20 | 2026-05-20 | 0001104659-26-064545 ↗ |
| 10-Q | 2026-05-12 | 2026-03-31 | 0001104659-26-059035 ↗ |
| 8-K | 2026-05-12 | 2026-05-12 | 0001104659-26-058967 ↗ |
| 10-K | 2026-03-25 | 2025-12-31 | 0001104659-26-034554 ↗ |
| 8-K | 2026-03-25 | 2026-03-25 | 0001104659-26-034162 ↗ |
| 8-K | 2026-01-30 | 2026-01-29 | 0001104659-26-008325 ↗ |
| 8-K | 2025-12-16 | 2025-12-12 | 0001104659-25-121627 ↗ |
| 8-K | 2025-11-24 | 2025-11-24 | 0001104659-25-115182 ↗ |
| 8-K | 2025-11-19 | 2025-11-17 | 0001104659-25-113978 ↗ |
| 10-Q | 2025-11-12 | 2025-09-30 | 0001104659-25-109719 ↗ |
| 8-K | 2025-11-12 | 2025-11-12 | 0001104659-25-109714 ↗ |
| 8-K | 2025-10-24 | 2025-10-22 | 0001104659-25-102137 ↗ |