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Travere Therapeutics, Inc.

TVTX · Pharmaceutical Preparations · 93.0M shares · +15%/yr ↑ dilution · EDGAR filings ↗
Net buyback after stock comp: -$42M (gross $2M, SBC $44M)

Reference price $50.00 · est. market cap ~$4.6B — last insider sale, 2026-06-12 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)

Grade

C58

Rare-kidney-disease company with a fast-growing approved IgAN drug but a failed FSGS confirmatory endpoint and continued losses.

Strengths

Risks

Notable findings

Quarterly revenue

2025-06-30 · $114M2025-09-30 · $165M2025-12-31 · $130M2026-03-31 · $127M

Last 4 quarters · from SEC filings.

Key metrics

Gross margin
97.9%
Operating margin
-12.8%
Net margin
-5.2%
Return on equity
-22.2%
Return on assets
-4.2%
Revenue growth (QoQ)
-1.9%
Current ratio
2.7×
EBITDA
-$2M
Tangible book value
$960K
Cash & investments
$323M
Stock comp / revenue
9.1%

Insider transactions · last 18 months

DateInsiderTypeSharesPrice
2026-06-22Inrig JulaGift468
2026-06-12Baynes Roy D.Option exercise4.5K$21.38
2026-06-12Coughlin TimothyOption exercise10K$26.52
2026-06-12Coughlin TimothySell10K$50.07
2026-06-12Baynes Roy D.Sell4.5K$50.00
2026-05-19Coughlin TimothyGrant4.0K
2026-05-19Baynes Roy D.Grant4.0K
2026-05-19Poole SandraGrant4.0K
2026-05-19Bruhn Suzanne LouiseGrant4.0K
2026-05-19Meckler Jeffrey AGrant4.0K
2026-05-19Orwin John AGrant4.0K
2026-05-19Squarer RonGrant4.0K
2026-05-19Williams Brinkley RuthGrant4.0K
2026-05-19LYONS GARY AGrant4.0K
2026-05-15Coughlin TimothySell3.2K$43.49
2026-05-06REED ELIZABETH ESell2.1K$43.95
2026-05-06Dube Eric MSell22K$43.95
2026-05-06ROTE WILLIAM E.Sell2.8K$43.95
2026-05-06Cline Christopher R.Sell310$43.95
2026-05-06Inrig JulaSell311$43.95
2026-05-05Heerma PeterSell2.2K$46.65
2026-05-05Cline Christopher R.Sell2.2K$46.65
2026-05-05Baynes Roy D.Sell4.5K$46.65
2026-05-05REED ELIZABETH ESell2.2K$46.65
2026-05-05Baynes Roy D.Option exercise4.5K$18.27
2026-05-05Inrig JulaSell2.2K$46.65
2026-05-04REED ELIZABETH EOption exercise20K$17.96
2026-05-04Cline Christopher R.Option exercise4.2K
2026-05-04Inrig JulaOption exercise20K$22.40
2026-05-04Inrig JulaSell20K$45.00
2026-05-04Inrig JulaOption exercise4.2K
2026-05-04Heerma PeterOption exercise4.2K
2026-05-04Dube Eric MOption exercise22K
2026-05-04ROTE WILLIAM E.Option exercise4.2K
2026-05-04Meckler Jeffrey AOption exercise8.0K$16.33
2026-05-04Meckler Jeffrey ASell8.0K$45.00
2026-05-04REED ELIZABETH ESell20K$45.00
2026-05-04REED ELIZABETH EOption exercise4.2K
2026-05-01Baynes Roy D.Sell9.8K$44.22
2026-05-01Baynes Roy D.Option exercise9.8K$6.82
2026-04-22ROTE WILLIAM E.Sell9.1K$39.09
2026-04-15Cline Christopher R.Sell1.0K$42.61
2026-04-15Inrig JulaSell1.0K$42.61
2026-04-15Dube Eric MSell57K$41.01
2026-04-15Dube Eric MSell7.2K$41.75
2026-04-15Dube Eric MSell20$42.66
2026-04-15REED ELIZABETH ESell5.2K$41.62
2026-04-15REED ELIZABETH ESell1.6K$42.53
2026-04-14Baynes Roy D.Sell6.8K$42.12
2026-04-14LYONS GARY AOption exercise8.0K$16.33
2026-04-14REED ELIZABETH EOption exercise10K$19.08
2026-04-14REED ELIZABETH EOption exercise20K$17.96
2026-04-14REED ELIZABETH EOption exercise7.5K$15.46
2026-04-14REED ELIZABETH ESell38K$41.07
2026-04-14REED ELIZABETH ESell7.2K$41.93
2026-04-14LYONS GARY ASell8.0K$41.07
2026-04-14Baynes Roy D.Option exercise4.5K$18.27
2026-04-14Baynes Roy D.Option exercise4.5K$21.38
2026-04-14Cline Christopher R.Sell9$41.07
2026-04-14Cline Christopher R.Sell7.2K$41.93
2026-04-14Baynes Roy D.Option exercise8.0K$17.94
2026-04-14Baynes Roy D.Option exercise6.8K$17.11
2026-04-14Inrig JulaSell7.2K$41.93
2026-04-14Calvin SandraSell22K$41.07
2026-04-14Baynes Roy D.Sell26K$41.07
2026-04-14Heerma PeterSell7.2K$41.93
2026-04-14Baynes Roy D.Option exercise9.0K$15.43
2026-04-14Calvin SandraOption exercise6.5K$20.46
2026-04-14Calvin SandraOption exercise6.2K$8.93
2026-04-14Calvin SandraOption exercise2.5K$22.40
2026-04-13Dube Eric MGrant64K
2026-04-13Cline Christopher R.Grant14K
2026-04-13Cline Christopher R.Sell65$28.85
2026-04-13Inrig JulaGrant14K
2026-04-13Heerma PeterGrant14K
2026-04-13ROTE WILLIAM E.Grant14K
2026-04-13REED ELIZABETH EGrant14K
2026-04-06Baynes Roy D.Option exercise10K$26.52
2026-04-06Baynes Roy D.Sell10K$33.00
2026-04-01Dube Eric MOption exercise60K$15.46
2026-04-01Dube Eric MSell35K$30.55
2026-04-01Dube Eric MSell25K$31.46
2026-04-01REED ELIZABETH EOption exercise10K$15.46
2026-04-01REED ELIZABETH ESell10K$30.00
2026-03-16REED ELIZABETH EOption exercise10K$19.08
2026-03-16REED ELIZABETH ESell10K$28.09
2026-02-20Dube Eric MSell60K$30.10
2026-02-20Dube Eric MOption exercise60K$15.46
2026-02-17REED ELIZABETH EOption exercise10K$19.08
2026-02-17REED ELIZABETH ESell5.7K$27.50
2026-02-17REED ELIZABETH ESell4.3K$28.26
2026-02-04REED ELIZABETH ESell2.5K$32.07
2026-02-04Inrig JulaSell232$32.85
2026-02-04Inrig JulaSell1.5K$32.11
2026-02-04Cline Christopher R.Sell110$32.90
2026-02-04Cline Christopher R.Sell1.6K$32.14
2026-02-04REED ELIZABETH ESell509$32.74
2026-02-03ROTE WILLIAM E.Sell12K$32.87
2026-02-03Cline Christopher R.Sell7.2K$32.12
2026-02-03Inrig JulaSell7.0K$32.12
2026-02-03Calvin SandraSell4.3K$32.12
2026-02-03Heerma PeterSell7.3K$32.12
2026-02-03Dube Eric MSell66K$32.06
2026-02-03Dube Eric MSell34K$32.70
2026-02-03REED ELIZABETH ESell7.2K$32.12
2026-01-31ROTE WILLIAM E.Grant20K
2026-01-31Inrig JulaGrant28K
2026-01-31Dube Eric MGrant114K
2026-01-31Calvin SandraGrant15K
2026-01-31Cline Christopher R.Grant28K
2026-01-31Heerma PeterGrant26K
2026-01-31REED ELIZABETH EGrant25K
2026-01-27Dube Eric MSell52K$30.10
2026-01-27Dube Eric MOption exercise52K$15.46
2026-01-23Dube Eric MOption exercise8.1K$15.46
2026-01-23Dube Eric MSell8.1K$30.01
2026-01-20REED ELIZABETH EOption exercise10K$19.08
2026-01-20REED ELIZABETH ESell10K$27.34
2026-01-06Inrig JulaSell445$37.75
2026-01-05Inrig JulaSell2.0K$40.18
2025-12-24Inrig JulaOption exercise15K$8.93
2025-12-24Inrig JulaSell15K$42.00
2025-12-24Calvin SandraSell7.4K$40.00
2025-12-24Heerma PeterSell5.0K$40.00
2025-12-24ROTE WILLIAM E.Option exercise60K$20.61
2025-12-24ROTE WILLIAM E.Sell60K$40.10
2025-12-15Calvin SandraSell2.9K$36.00
2025-12-01Cline Christopher R.Option exercise20K$16.23
2025-12-01Cline Christopher R.Sell20K$35.01
2025-11-04Calvin SandraOption exercise10K$25.25
2025-11-04Calvin SandraOption exercise18K$26.88
2025-11-04Calvin SandraOption exercise15K$27.50
2025-11-04Calvin SandraOption exercise12K$22.40
2025-11-04Calvin SandraOption exercise6.2K$8.93
2025-11-04Calvin SandraSell67K$36.00
2025-11-03Heerma PeterGift1.1K
2025-10-31Heerma PeterSell5.6K$35.00
2025-10-31Coughlin TimothyOption exercise8.0K$16.33
2025-10-31Coughlin TimothyOption exercise10K$17.44
2025-10-31Coughlin TimothySell18K$35.03
2025-10-29Dube Eric MOption exercise27K$15.46
2025-10-29Dube Eric MSell27K$30.12
2025-10-28Dube Eric MOption exercise93K$15.46
2025-10-28Heerma PeterSell2.7K$30.00
2025-10-28Dube Eric MSell93K$30.38
2025-09-23Heerma PeterGift891
2025-09-22REED ELIZABETH EOption exercise10K$19.08
2025-09-22REED ELIZABETH ESell10K$25.00
2025-09-04Cline Christopher R.Sell119$19.71
2025-09-03Cline Christopher R.Sell454$18.20
2025-08-27Cline Christopher R.Sell470$17.31
2025-07-01Inrig JulaSell815$14.65
2025-05-15Squarer RonGrant6.5K
2025-05-15Williams Brinkley RuthGrant6.5K
2025-05-15Poole SandraGrant6.5K
2025-05-15Orwin John AGrant6.5K
2025-05-15Meckler Jeffrey AGrant6.5K
2025-05-15LYONS GARY AGrant6.5K
2025-05-15COUGHLIN TIMOTHYGrant6.5K
2025-05-15Bruhn Suzanne LouiseGrant6.5K
2025-05-15Baynes Roy D.Grant6.5K
2025-05-05Heerma PeterSell1.8K$21.05
2025-05-05Cline Christopher R.Sell1.8K$21.05
2025-05-05REED ELIZABETH ESell4.9K$21.05
2025-05-05Dube Eric MSell19K$21.05
2025-05-05ROTE WILLIAM E.Sell3.2K$21.05
2025-05-02Cline Christopher R.Option exercise4.9K
2025-05-02Dube Eric MOption exercise19K
2025-05-02Heerma PeterOption exercise4.9K
2025-05-02ROTE WILLIAM E.Option exercise4.9K
2025-05-02REED ELIZABETH EOption exercise4.9K
2025-04-11Cline Christopher R.Sell48$13.14
2025-02-12Inrig JulaSell2.6K$23.53
2025-02-12ROTE WILLIAM E.Sell5.2K$23.53
2025-02-12Heerma PeterSell2.6K$23.53
2025-02-12REED ELIZABETH ESell8.0K$23.53
2025-02-11Calvin SandraOption exercise10K$17.96
2025-02-11Calvin SandraSell10K$25.00
2025-02-11Calvin SandraSell15K$25.00
2025-02-11Calvin SandraSell9.2K$25.00
2025-02-11Calvin SandraOption exercise15K$15.46
2025-02-11Calvin SandraOption exercise10K$16.23
2025-02-11Calvin SandraSell10K$25.00
2025-02-11Calvin SandraOption exercise10K$17.44
2025-02-11Calvin SandraSell10K$25.00
2025-02-11Heerma PeterSell3.1K$25.00
2025-02-11Dube Eric MSell11K$24.04
2025-02-10ROTE WILLIAM E.Option exercise8.0K
2025-02-10Inrig JulaOption exercise8.0K
2025-02-10REED ELIZABETH EOption exercise8.0K
2025-02-10Heerma PeterOption exercise8.0K
2025-02-06Baynes Roy D.Option exercise10K$17.44
2025-02-06Baynes Roy D.Sell10K$22.00
2025-02-04Inrig JulaSell1.1K$20.11
2025-02-03ROTE WILLIAM E.Sell9.0K$19.78
2025-02-03REED ELIZABETH ESell9.0K$19.78
2025-02-03Dube Eric MSell51K$20.21
2025-02-03Inrig JulaSell4.2K$20.12
2025-02-03Heerma PeterSell5.2K$20.12
2025-02-03Cline Christopher R.Sell5.2K$20.12
2025-02-03Calvin SandraSell3.3K$20.12
2025-01-31ROTE WILLIAM E.Grant22K
2025-01-31Heerma PeterGrant22K
2025-01-31Calvin SandraGrant13K
2025-01-31REED ELIZABETH EGrant22K
2025-01-31Inrig JulaGrant30K
2025-01-31Dube Eric MGrant130K
2025-01-31Cline Christopher R.Grant22K
2025-01-23Baynes Roy D.Option exercise16K$17.50
2025-01-23Baynes Roy D.Sell16K$20.00
2025-01-22Dube Eric MSell11K$19.46
2025-01-22Heerma PeterSell1.6K$18.94
2025-01-22Calvin SandraSell925$18.94
2025-01-22Cline Christopher R.Sell865$18.94
2025-01-22ROTE WILLIAM E.Sell2.4K$19.46
2025-01-22REED ELIZABETH ESell2.4K$19.46
2025-01-06Inrig JulaSell440$18.76
2025-01-03Inrig JulaSell2.1K$19.10

All non-derivative Form 4 activity (SEC), newest first.

Clinical trials

TrialTitlePhaseStatusPrimary completion
NCT06431893 ↗A Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)
Homocystinuria
PHASE3Enrolling By Invitation2030-08-01
NCT06247085 ↗A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment
Homocystinuria
PHASE3Recruiting2027-08-01
NCT05003986 ↗Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
Focal Segmental Glomerulosclerosis, Minimal Change Disease
PHASE2Recruiting2027-03-12
NCT07219121 ↗Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis
Proteinuria, Immunoglobulin A (IgA) Nephropathy
PHASE4Active Not Recruiting2027-03-01
NCT03406611 ↗Pegtibatinase As an Enzyme Therapy for Patients with Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (COMPOSE)
Homocystinuria
PHASE1/PHASE2Active Not Recruiting2026-06-01
NCT02998710 ↗Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)
Homocystinuria Due to CBS Deficiency
Recruiting2026-04-01
NCT03762850 ↗A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA Nephropathy
Immunoglobulin A Nephropathy
PHASE3Active Not Recruiting2023-08-07
NCT05856760 ↗A Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in Participants With IgAN
Immunoglobulin A Nephropathy
PHASE2Completed2024-10-14
NCT05200871 ↗Humanistic Burden of (FSGS) Focal Segmental Glomerulosclerosis and IgAN (Immunoglobulin A Nephropathy)
Focal Segmental Glomerulosclerosis, Immunoglobulin A Nephropathy
Completed2023-10-31
NCT03493685 ↗Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS)
Focal Segmental Glomerulosclerosis
PHASE3Completed2023-03-20
NCT02638220 ↗Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Cerebrotendinous Xanthomatosis (CTX)
Completed2021-02-19
NCT05562362 ↗Study to Evaluate the Pharmacokinetics of Oral Sparsentan Suspension
Healthy Subjects
PHASE1Completed2020-11-12
NCT03041116 ↗Efficacy and Safety Study of Fosmetpantotenate (RE-024) in PKAN Participants
Pantothenate Kinase-Associated Neurodegeneration
PHASE3Terminated2019-12-30
NCT01613118 ↗Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis
Focal Segmental Glomerulosclerosis
PHASE2Completed2016-06-01

Source: ClinicalTrials.gov (U.S. NIH) · active studies first.

Supply chain

Customers (0)

    Named in the 10-K; linked when we track them.

    Notable events (8-K)

    DateItems
    2026-06-16Exec/director changefiling ↗
    2026-06-02Material agreementExhibitsfiling ↗
    2026-05-21Exec/director changeShareholder voteExhibitsfiling ↗
    2026-05-11Material agreementDebt obligation3.02OtherExhibitsfiling ↗
    2026-05-04ResultsExhibitsfiling ↗
    2026-04-14Otherfiling ↗
    2026-02-19ResultsExhibitsfiling ↗
    2026-01-13Otherfiling ↗

    Recent filings

    FormFiledPeriodAccession
    8-K2026-06-162026-06-120001438533-26-000048 ↗
    8-K2026-06-022026-06-010001193125-26-252474 ↗
    8-K2026-05-212026-05-190001438533-26-000046 ↗
    8-K2026-05-112026-05-060001193125-26-217100 ↗
    10-Q2026-05-042026-03-310001438533-26-000042 ↗
    8-K2026-05-042026-05-040001438533-26-000041 ↗
    8-K2026-04-142026-04-130001438533-26-000032 ↗
    10-K2026-02-192025-12-310001438533-26-000014 ↗
    8-K2026-02-192026-02-190001438533-26-000013 ↗
    8-K2026-01-132026-01-130001438533-26-000005 ↗
    8-K2026-01-122026-01-120001438533-26-000003 ↗
    10-Q2025-10-302025-09-300001438533-25-000056 ↗