uniQure N.V.
QURE · Pharmaceutical Preparations · 63.1M shares · +4%/yr ↑ dilution · EDGAR filings ↗
Reference price $50.02 · est. market cap ~$3.2B — last insider sale, 2026-06-25 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)
Grade
D46Clinical/early-stage biotech — gene-therapy clinical, heavy burn ($178M), very well-funded.
Strengths
- Liquidity — current ratio 10.4 (80th)
Risks
- Pre-revenue, deep losses — per metrics
- Pre-revenue/clinical-stage — history of losses & need for capital per risk factors
- Binary clinical & funding risk — per 10-K
Notable findings
Quarterly revenue
Last 4 quarters · from SEC filings.
Key metrics
Return on equity
-100.0%
Return on assets
-24.1%
ROIC
-58.9%
Revenue growth (QoQ)
127.3%
Debt / equity
0.2×
Current ratio
10.4×
Free cash flow
-$178M
EBITDA
-$171M
Tangible book value
$101M
Cash & investments
$80M
Cash runway
2q
Insider transactions · last 18 months
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| 2026-06-25 | Kapusta Matthew C | Sell | 29K | $50.02 |
| 2026-06-25 | Kapusta Matthew C | Option exercise | 29K | $31.71 |
| 2026-06-24 | Kapusta Matthew C | Sell | 6.7K | $50.00 |
| 2026-06-24 | Kapusta Matthew C | Option exercise | 4.1K | $31.71 |
| 2026-06-18 | Kapusta Matthew C | Option exercise | 4.7K | $31.71 |
| 2026-06-18 | Kapusta Matthew C | Sell | 37K | $50.00 |
| 2026-06-18 | Kapusta Matthew C | Sell | 4.7K | $50.00 |
| 2026-06-17 | Balachandran Madhavan | Sell | 5.3K | $47.08 |
| 2026-06-17 | Balachandran Madhavan | Sell | 4.7K | $43.66 |
| 2026-06-17 | Balachandran Madhavan | Sell | 1.7K | $42.60 |
| 2026-06-17 | Kaye Jack | Option exercise | 5.3K | $31.71 |
| 2026-06-17 | Kaye Jack | Sell | 5.3K | $42.57 |
| 2026-06-17 | Balachandran Madhavan | Option exercise | 5.3K | $31.71 |
| 2026-06-17 | Kapusta Matthew C | Sell | 33K | $45.02 |
| 2026-06-17 | Kapusta Matthew C | Sell | 6.0K | $43.70 |
| 2026-06-17 | Kapusta Matthew C | Sell | 24K | $42.61 |
| 2026-06-17 | Kapusta Matthew C | Option exercise | 63K | $19.39 |
| 2026-06-17 | Balachandran Madhavan | Option exercise | 6.4K | $19.39 |
| 2026-06-17 | Kapusta Matthew C | Sell | 57K | $43.43 |
| 2026-06-17 | Kapusta Matthew C | Sell | 33K | $45.01 |
| 2026-06-17 | Kapusta Matthew C | Sell | 12K | $48.65 |
| 2026-06-15 | Balachandran Madhavan | Sell | 10K | $27.85 |
| 2026-06-15 | Potts Jeannette | Sell | 5.2K | $27.67 |
| 2026-06-15 | Balachandran Madhavan | Option exercise | 10K | $8.49 |
| 2026-06-11 | Jacques Rachelle Suzanne | Sell | 2.0K | $27.06 |
| 2026-06-11 | Springhorn Jeremy P. | Sell | 2.0K | $27.06 |
| 2026-06-11 | Meek David D. | Sell | 2.0K | $27.06 |
| 2026-06-11 | Gut Robert | Sell | 2.7K | $27.06 |
| 2026-06-11 | O'Keefe Kylie | Sell | 16K | $27.06 |
| 2026-06-11 | Kaye Jack | Sell | 2.0K | $27.06 |
| 2026-06-11 | POST LEONARD E | Sell | 2.0K | $27.06 |
| 2026-06-11 | Balachandran Madhavan | Sell | 2.0K | $27.06 |
| 2026-06-10 | POST LEONARD E | Grant | 7.5K | — |
| 2026-06-10 | Meek David D. | Grant | 7.5K | — |
| 2026-06-10 | Gut Robert | Option exercise | 2.6K | $16.04 |
| 2026-06-10 | Gut Robert | Sell | 2.6K | $26.07 |
| 2026-06-10 | Gut Robert | Sell | 3.1K | $26.03 |
| 2026-06-10 | Gut Robert | Sell | 1.8K | $26.05 |
| 2026-06-10 | Gut Robert | Grant | 7.5K | — |
| 2026-06-10 | Springhorn Jeremy P. | Grant | 7.5K | — |
| 2026-06-10 | Kaye Jack | Grant | 7.5K | — |
| 2026-06-10 | Jacques Rachelle Suzanne | Grant | 7.5K | — |
| 2026-06-10 | Balachandran Madhavan | Grant | 7.5K | — |
| 2026-06-03 | Kaye Jack | Sell | 2.6K | $30.01 |
| 2026-06-03 | Kaye Jack | Option exercise | 2.6K | $16.04 |
| 2026-05-08 | Abi-Saab Walid | Sell | 20K | $25.00 |
| 2026-05-08 | Abi-Saab Walid | Sell | 25K | $25.10 |
| 2026-05-08 | Abi-Saab Walid | Option exercise | 25K | $5.59 |
| 2026-03-04 | Abi-Saab Walid | Sell | 808 | $9.06 |
| 2026-03-04 | Potts Jeannette | Grant | 35K | — |
| 2026-03-04 | Potts Jeannette | Sell | 3.4K | $9.06 |
| 2026-03-04 | KLEMT CHRISTIAN | Grant | 40K | — |
| 2026-03-04 | KLEMT CHRISTIAN | Sell | 12K | $9.06 |
| 2026-03-04 | Kapusta Matthew C | Grant | 71K | — |
| 2026-03-04 | O'Keefe Kylie | Grant | 20K | — |
| 2026-03-04 | Kapusta Matthew C | Sell | 15K | $9.06 |
| 2026-03-04 | Abi-Saab Walid | Grant | 42K | — |
| 2026-03-02 | Kapusta Matthew C | Sell | 34K | $9.95 |
| 2026-03-02 | KLEMT CHRISTIAN | Sell | 13K | $9.95 |
| 2026-03-02 | Potts Jeannette | Sell | 8.6K | $9.95 |
| 2026-03-02 | Abi-Saab Walid | Sell | 1.7K | $9.95 |
| 2026-02-25 | Kapusta Matthew C | Sell | 12K | $23.86 |
| 2026-02-25 | KLEMT CHRISTIAN | Sell | 6.2K | $23.86 |
| 2026-01-12 | Gut Robert | Option exercise | 18K | $14.08 |
| 2026-01-12 | Gut Robert | Sell | 17K | $24.39 |
| 2026-01-12 | Gut Robert | Sell | 500 | $25.03 |
| 2026-01-12 | Gut Robert | Sell | 7.8K | $25.09 |
| 2026-01-09 | Kaye Jack | Option exercise | 6.4K | $19.39 |
| 2026-01-09 | Kaye Jack | Sell | 6.4K | $27.28 |
| 2025-11-06 | Gut Robert | Sell | 16K | $27.22 |
| 2025-11-06 | Gut Robert | Sell | 16K | $27.30 |
| 2025-11-06 | Gut Robert | Option exercise | 16K | $4.57 |
| 2025-11-04 | Kaye Jack | Option exercise | 18K | $14.08 |
| 2025-11-04 | Kaye Jack | Sell | 18K | $30.33 |
| 2025-11-04 | Kaye Jack | Option exercise | 10K | $7.37 |
| 2025-11-04 | Kaye Jack | Sell | 10K | $30.36 |
| 2025-11-04 | Kaye Jack | Option exercise | 11K | $5.37 |
| 2025-11-04 | Kaye Jack | Sell | 11K | $30.34 |
| 2025-09-26 | KLEMT CHRISTIAN | Option exercise | 15K | $5.37 |
| 2025-09-26 | KLEMT CHRISTIAN | Sell | 15K | $55.00 |
| 2025-09-24 | Kapusta Matthew C | Sell | 60K | $45.10 |
| 2025-09-24 | KLEMT CHRISTIAN | Option exercise | 3.0K | $13.03 |
| 2025-09-24 | KLEMT CHRISTIAN | Sell | 3.0K | $40.04 |
| 2025-09-24 | Kapusta Matthew C | Sell | 50K | $40.68 |
| 2025-09-24 | Kapusta Matthew C | Sell | 5.0K | $41.69 |
| 2025-09-24 | Kapusta Matthew C | Option exercise | 51K | $7.53 |
| 2025-09-24 | Kapusta Matthew C | Option exercise | 175K | $6.22 |
| 2025-09-24 | Kapusta Matthew C | Sell | 51K | $39.59 |
| 2025-09-24 | Kapusta Matthew C | Sell | 60K | $40.04 |
| 2025-06-27 | Abi-Saab Walid | Sell | 1.5K | $13.92 |
| 2025-06-20 | Gut Robert | Sell | 3.3K | $14.45 |
| 2025-06-20 | Balachandran Madhavan | Sell | 2.1K | $14.45 |
| 2025-06-20 | Meek David D. | Sell | 2.1K | $14.45 |
| 2025-06-20 | Springhorn Jeremy P. | Sell | 2.1K | $14.45 |
| 2025-06-20 | POST LEONARD E | Sell | 2.1K | $14.45 |
| 2025-06-20 | Jacques Rachelle Suzanne | Sell | 2.1K | $14.45 |
| 2025-06-20 | Kaye Jack | Sell | 2.1K | $14.45 |
| 2025-06-16 | Potts Jeannette | Sell | 4.7K | $15.14 |
| 2025-06-11 | Balachandran Madhavan | Grant | 8.0K | — |
| 2025-06-11 | Springhorn Jeremy P. | Grant | 8.0K | — |
| 2025-06-11 | Meek David D. | Grant | 8.0K | — |
| 2025-06-11 | Gut Robert | Grant | 8.0K | — |
| 2025-06-11 | Jacques Rachelle Suzanne | Grant | 8.0K | — |
| 2025-06-11 | Kaye Jack | Grant | 8.0K | — |
| 2025-06-11 | POST LEONARD E | Grant | 8.0K | — |
| 2025-03-04 | Abi-Saab Walid | Sell | 1.4K | $10.29 |
| 2025-03-04 | Kapusta Matthew C | Sell | 28K | $10.29 |
| 2025-03-04 | KLEMT CHRISTIAN | Sell | 10K | $10.29 |
| 2025-03-04 | Potts Jeannette | Sell | 7.1K | $10.29 |
| 2025-03-03 | KLEMT CHRISTIAN | Grant | 73K | — |
| 2025-03-03 | Potts Jeannette | Grant | 35K | — |
| 2025-03-03 | Kapusta Matthew C | Grant | 99K | — |
| 2025-03-03 | Abi-Saab Walid | Grant | 38K | — |
| 2025-02-27 | KLEMT CHRISTIAN | Sell | 2.9K | $11.32 |
| 2025-02-27 | Kapusta Matthew C | Sell | 6.7K | $11.32 |
| 2025-02-26 | KLEMT CHRISTIAN | Grant | 5.7K | — |
| 2025-02-26 | Kapusta Matthew C | Grant | 16K | — |
| 2025-02-25 | Kapusta Matthew C | Sell | 27K | $10.70 |
| 2025-02-25 | KLEMT CHRISTIAN | Sell | 14K | $10.70 |
All non-derivative Form 4 activity (SEC), newest first.
Notable events (8-K)
| Date | Items | |
|---|---|---|
| 2026-06-24 | Material agreementOtherExhibits | filing ↗ |
| 2026-06-22 | Reg FDOtherExhibits | filing ↗ |
| 2026-06-17 | OtherExhibits | filing ↗ |
| 2026-06-15 | Exec/director change5.03Shareholder voteExhibits | filing ↗ |
| 2026-05-05 | ResultsExhibits | filing ↗ |
| 2026-04-30 | Reg FDExhibits | filing ↗ |
| 2026-03-02 | ResultsReg FDExhibits | filing ↗ |
| 2026-01-13 | Reg FDExhibits | filing ↗ |
Recent filings
| Form | Filed | Period | Accession |
|---|---|---|---|
| 8-K | 2026-06-24 | 2026-06-23 | 0001104659-26-077339 ↗ |
| 8-K | 2026-06-22 | 2026-06-19 | 0001104659-26-076044 ↗ |
| 8-K | 2026-06-17 | 2026-06-17 | 0001104659-26-074853 ↗ |
| 8-K | 2026-06-15 | 2026-06-10 | 0001104659-26-074067 ↗ |
| 8-K | 2026-05-05 | 2026-05-05 | 0001104659-26-055242 ↗ |
| 10-Q | 2026-05-05 | 2026-03-31 | 0001104659-26-055250 ↗ |
| 8-K | 2026-04-30 | 2026-04-30 | 0001104659-26-052112 ↗ |
| 8-K | 2026-03-02 | 2026-03-02 | 0001104659-26-021890 ↗ |
| 10-K | 2026-03-02 | 2025-12-31 | 0001104659-26-021898 ↗ |
| 8-K | 2026-01-13 | 2026-01-13 | 0001104659-26-003075 ↗ |
| 8-K | 2026-01-09 | 2026-01-09 | 0001104659-26-002317 ↗ |
| 8-K | 2025-12-04 | 2025-12-04 | 0001104659-25-118292 ↗ |