BeOne Medicines Ltd.

ONC, BEIGF · Pharmaceutical Preparations · 1.45B shares · +15%/yr ↑ dilution · EDGAR filings ↗

Reference price $276.74 · est. market cap ~$400.0B — last insider sale, 2026-06-23 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)

Grade

B78

Global oncology biopharma (Brukinsa) — newly profitable with very strong free cash flow and growth.

Strengths

Very strong free cash flow — FCF $942M (96th), FCF margin 18%
Newly profitable, high gross margin — operating margin 8% (80th), gross margin 87%, ROA 4% (88th)

Risks

China-operations/geopolitical exposure — per 10-K
Competition in hematology-oncology — per 10-K
R&D-spend intensity — per 10-K

Notable findings

Exec changeRecent 8-K item 5.02 8-K ↗
Chronic dilutionShare count +15%/yr over 4y (dilution, book value/share -59%)
Strong balance sheetStrong balance sheet — $4.6B cash & investments
Insider sellingInsider selling — 45 open-market sale(s) by 11 insider(s) (cluster of 11 insiders, ~$9M, last 6mo) Form 4 ↗
AccumulatingInstitutional holders rose 10→11 QoQ (2025-12-31→2026-03-31)
Notable holderHeld by 5 notable fund(s): FMR LLC, CITADEL ADVISORS LLC, GOLDMAN SACHS GROUP INC +2 more (as of 2026-03-31)
New fund positionNotable fund(s) opened this quarter: RENAISSANCE TECHNOLOGIES LLC

Quarterly revenue

2025-06-30 · $1.3B2025-09-30 · $1.4B2025-12-31 · $1.5B2026-03-31 · $1.5B

Last 4 quarters · from SEC filings.

Key metrics

Gross margin

87.5%

Operating margin

8.4%

Net margin

5.4%

Return on equity

6.6%

Return on assets

3.5%

ROIC

6.6%

Revenue growth (QoQ)

1.0%

Debt / equity

0.2×

Net debt / EBITDA

-6.2×

Current ratio

3.4×

Free cash flow

$942M

EBITDA

$589M

Tangible book value

$4.3B

Cash & investments

$4.6B

Stock comp / revenue

9.6%

Insider transactions · last 18 months

Date	Insider	Type	Shares	Price
2026-06-23	Wu Xiaobin	Sell	1.3K	$276.26
2026-06-23	Wang Lai	Sell	1.1K	$276.74
2026-06-23	OYLER JOHN	Sell	320	$275.10
2026-06-23	OYLER JOHN	Sell	1.3K	$274.12
2026-06-23	OYLER JOHN	Sell	1.8K	$273.30
2026-06-16	Wu Xiaobin	Sell	1.4K	$266.76
2026-06-16	Wang Lai	Sell	1.2K	$265.39
2026-06-16	Lee Chan Henry	Sell	590	$265.98
2026-06-16	OYLER JOHN	Sell	333	$266.69
2026-06-16	OYLER JOHN	Sell	1.7K	$265.99
2026-06-16	OYLER JOHN	Sell	1.6K	$264.87
2026-06-11	Rosenberg Aaron	Sell	631	$257.74
2026-06-11	Mooney Elizabeth Fisher	Grant	19K	—
2026-06-11	Sawyers Charles Lazelle	Grant	19K	—
2026-06-11	Rosenberg Aaron	Grant	71K	—
2026-06-11	Lee Chan Henry	Grant	45K	—
2026-06-11	Lee Chan Henry	Sell	428	$257.63
2026-06-11	Dugan Margaret	Grant	19K	—
2026-06-11	Riva Alessandro	Grant	19K	—
2026-06-11	Wang Lai	Grant	119K	—
2026-06-11	Wang Lai	Sell	756	$261.00
2026-06-11	Wu Xiaobin	Grant	119K	—
2026-06-11	Wu Xiaobin	Sell	626	$261.20
2026-06-11	Ball Titus B.	Grant	31K	—
2026-06-11	Ball Titus B.	Sell	49	$256.39
2026-06-11	Ball Titus B.	Sell	120	$257.53
2026-06-11	Wang Xiaodong	Grant	100K	—
2026-06-11	BRANDICOURT OLIVIER	Grant	19K	—
2026-06-11	Sharp Shalini	Grant	19K	—
2026-06-11	HOOPER ANTHONY C	Grant	19K	—
2026-06-11	BAKER BROS. ADVISORS LP	Grant	19K	—
2026-06-11	BAKER BROS. ADVISORS LP	Grant	19K	—
2026-06-11	OYLER JOHN	Grant	178K	—
2026-06-11	OYLER JOHN	Sell	741	$256.23
2026-06-11	OYLER JOHN	Sell	859	$257.59
2026-06-11	OYLER JOHN	Sell	200	$258.28
2026-06-11	OYLER JOHN	Sell	149	$258.81
2026-06-08	Ball Titus B.	Sell	100	$271.06
2026-06-08	Ball Titus B.	Sell	36	$272.08
2026-06-08	Lee Chan Henry	Sell	711	$270.24
2026-06-08	Lee Chan Henry	Sell	160	$271.26
2026-06-08	Wang Lai	Sell	1.3K	$269.34
2026-06-08	Wang Lai	Sell	40	$270.73
2026-06-08	OYLER JOHN	Sell	1.1K	$271.14
2026-06-08	Wu Xiaobin	Sell	1.4K	$269.33
2026-06-08	Wu Xiaobin	Sell	40	$270.55
2026-06-08	OYLER JOHN	Sell	3.8K	$270.38
2026-06-01	Yi Qingqing	Sell	235	$279.13
2026-05-22	BAKER BROS. ADVISORS LP	Sell	2.8K	$23.79
2026-05-22	Sanders Corazon (Corsee) D.	Sell	212	$309.59
2026-05-22	BAKER BROS. ADVISORS LP	Sell	2.7K	$23.85
2026-05-22	BAKER BROS. ADVISORS LP	Sell	2.7K	$23.85
2026-05-22	BAKER BROS. ADVISORS LP	Sell	2.8K	$23.79
2026-05-22	Dugan Margaret	Sell	212	$309.60
2026-05-22	Riva Alessandro	Sell	212	$309.51
2026-05-13	Lee Chan Henry	Option exercise	133	$213.32
2026-05-13	Lee Chan Henry	Option exercise	98	$159.03
2026-05-13	Lee Chan Henry	Sell	332	$310.72
2026-05-13	Lee Chan Henry	Option exercise	101	$194.47
2026-04-08	Lee Chan Henry	Sell	332	$311.59
2026-04-08	Lee Chan Henry	Option exercise	101	$194.47
2026-04-08	Lee Chan Henry	Option exercise	133	$213.32
2026-04-08	Lee Chan Henry	Option exercise	98	$159.03
2026-03-11	Lee Chan Henry	Option exercise	110	$194.47
2026-03-11	Lee Chan Henry	Option exercise	98	$159.03
2026-03-11	Lee Chan Henry	Sell	341	$300.00
2026-03-11	Lee Chan Henry	Option exercise	133	$213.32
2026-03-06	Lee Chan Henry	Grant	30K	—
2026-03-06	Rosenberg Aaron	Grant	79K	—
2026-03-06	Rosenberg Aaron	Grant	41K	—
2026-03-06	Lee Chan Henry	Grant	65K	—
2026-03-06	Wu Xiaobin	Grant	169K	—
2026-03-06	Wang Lai	Grant	113K	—
2026-03-06	Wang Lai	Grant	55K	—
2026-03-06	OYLER JOHN	Grant	327K	—
2026-03-06	OYLER JOHN	Grant	118K	—
2026-03-06	Wu Xiaobin	Grant	79K	—
2026-02-04	Lee Chan Henry	Option exercise	502	$194.47
2026-02-04	Lee Chan Henry	Option exercise	662	$213.32
2026-02-04	Lee Chan Henry	Option exercise	496	$159.03
2026-02-04	Lee Chan Henry	Sell	664	$348.79
2026-02-04	Lee Chan Henry	Sell	996	$350.00
2026-01-07	Lee Chan Henry	Option exercise	202	$194.47
2026-01-07	Lee Chan Henry	Option exercise	266	$213.32
2026-01-07	Lee Chan Henry	Option exercise	196	$159.03
2026-01-07	Lee Chan Henry	Sell	664	$331.76
2025-12-31	Wang Lai	Grant	428K	—
2025-12-16	OYLER JOHN	Sell	1.9K	$300.80
2025-12-16	OYLER JOHN	Sell	40	$305.24
2025-12-16	OYLER JOHN	Sell	2.0K	$304.36
2025-12-16	OYLER JOHN	Sell	1.3K	$304.13
2025-12-16	OYLER JOHN	Sell	5.4K	$303.72
2025-12-16	OYLER JOHN	Sell	1.6K	$303.13
2025-12-16	OYLER JOHN	Sell	7.5K	$302.74
2025-12-16	OYLER JOHN	Sell	1.5K	$302.31
2025-12-16	OYLER JOHN	Sell	2.6K	$301.79
2025-12-16	OYLER JOHN	Sell	600	$300.98
2025-12-15	OYLER JOHN	Sell	2.3K	$311.33
2025-12-15	OYLER JOHN	Sell	1.8K	$301.58
2025-12-15	OYLER JOHN	Sell	6.4K	$302.29
2025-12-15	OYLER JOHN	Sell	1.9K	$303.60
2025-12-15	OYLER JOHN	Sell	5.8K	$304.37
2025-12-15	OYLER JOHN	Sell	3.9K	$305.55
2025-12-15	OYLER JOHN	Sell	4.9K	$306.39
2025-12-15	OYLER JOHN	Sell	5.1K	$307.38
2025-12-15	OYLER JOHN	Sell	14K	$308.41
2025-12-15	OYLER JOHN	Sell	11K	$309.37
2025-12-15	OYLER JOHN	Sell	16K	$310.48
2025-12-15	OYLER JOHN	Sell	121	$311.93
2025-12-15	OYLER JOHN	Sell	929	$313.52
2025-12-15	OYLER JOHN	Sell	1.2K	$314.92
2025-12-11	Lee Chan Henry	Option exercise	98	$159.03
2025-12-11	Lee Chan Henry	Sell	332	$325.00
2025-12-11	Lee Chan Henry	Option exercise	133	$213.32
2025-12-11	Lee Chan Henry	Option exercise	101	$194.47
2025-12-10	Lee Chan Henry	Sell	332	$318.28
2025-12-10	Lee Chan Henry	Option exercise	133	$213.32
2025-12-10	Lee Chan Henry	Option exercise	98	$159.03
2025-12-10	Lee Chan Henry	Option exercise	101	$194.47
2025-11-26	Sanders Corazon (Corsee) D.	Sell	804	$342.47
2025-11-26	Sanders Corazon (Corsee) D.	Option exercise	2.6K	$159.03
2025-11-26	Sanders Corazon (Corsee) D.	Sell	1.8K	$340.20
2025-11-17	Wu Xiaobin	Sell	10	$382.32
2025-11-17	Wu Xiaobin	Sell	3.2K	$380.23
2025-11-17	Wu Xiaobin	Sell	826	$381.19
2025-11-13	Wu Xiaobin	Sell	4.2K	$380.33
2025-11-13	Wu Xiaobin	Sell	1.8K	$381.05
2025-11-12	Wu Xiaobin	Sell	500	$350.44
2025-11-12	Lee Chan Henry	Option exercise	302	$194.47
2025-11-12	Lee Chan Henry	Option exercise	398	$213.32
2025-11-12	Lee Chan Henry	Option exercise	296	$159.03
2025-11-12	Lee Chan Henry	Sell	664	$348.75
2025-11-12	Lee Chan Henry	Sell	332	$350.00
2025-11-12	Wu Xiaobin	Sell	3.2K	$351.41
2025-11-12	Wu Xiaobin	Sell	789	$352.78
2025-11-12	Wu Xiaobin	Sell	251	$354.20
2025-11-12	Wu Xiaobin	Sell	120	$355.00
2025-11-12	Wu Xiaobin	Sell	100	$357.43
2025-11-12	Wu Xiaobin	Sell	4.8K	$360.10
2025-11-12	Wu Xiaobin	Sell	154	$362.07
2025-11-12	OYLER JOHN	Gift	859K	—
2025-11-11	OYLER JOHN	Gift	151K	—
2025-11-07	Wang Xiaodong	Gift	424K	—
2025-10-08	Lee Chan Henry	Option exercise	302	$194.47
2025-10-08	Lee Chan Henry	Sell	4.2K	$351.12
2025-10-08	Lee Chan Henry	Option exercise	296	$159.03
2025-10-08	Lee Chan Henry	Sell	664	$347.82
2025-10-08	Lee Chan Henry	Sell	4.7K	$350.22
2025-10-08	Lee Chan Henry	Option exercise	9.0K	$213.32
2025-10-08	Lee Chan Henry	Sell	1.1K	$350.00
2025-09-16	OYLER JOHN	Sell	12K	$326.14
2025-09-16	OYLER JOHN	Sell	4.1K	$324.12
2025-09-16	OYLER JOHN	Sell	6.9K	$325.06
2025-09-16	OYLER JOHN	Sell	4.0K	$326.90
2025-09-16	OYLER JOHN	Sell	400	$327.78
2025-09-10	Lee Chan Henry	Option exercise	1.8K	$213.32
2025-09-10	Lee Chan Henry	Option exercise	6.8K	$194.47
2025-09-10	Lee Chan Henry	Sell	4.8K	$325.19
2025-09-10	Lee Chan Henry	Option exercise	296	$159.03
2025-09-10	Lee Chan Henry	Sell	500	$327.93
2025-09-10	Lee Chan Henry	Sell	1.1K	$325.00
2025-09-10	Lee Chan Henry	Sell	300	$326.80
2025-09-10	Lee Chan Henry	Sell	3.3K	$325.73
2025-09-09	Wang Xiaodong	Gift	148K	—
2025-09-09	Wang Lai	Sell	5.0K	$350.06
2025-09-05	Sanders Corazon (Corsee) D.	Sell	2.7K	$337.00
2025-09-05	Sanders Corazon (Corsee) D.	Option exercise	2.7K	$155.68
2025-09-02	Ball Titus B.	Sell	122	$326.76
2025-08-14	Wu Xiaobin	Option exercise	31K	$155.68
2025-08-14	Wu Xiaobin	Sell	600	$308.03
2025-08-14	Wu Xiaobin	Sell	4.9K	$307.43
2025-08-14	Wu Xiaobin	Sell	12K	$306.26
2025-08-14	Wu Xiaobin	Sell	8.5K	$305.48
2025-08-14	Wu Xiaobin	Sell	500	$304.19
2025-08-14	Wu Xiaobin	Sell	7.0K	$303.31
2025-08-14	Wu Xiaobin	Sell	5.8K	$302.04
2025-08-14	Wu Xiaobin	Sell	400	$300.86
2025-08-14	Wu Xiaobin	Option exercise	9.2K	$159.03
2025-08-13	Wu Xiaobin	Sell	7.4K	$304.37
2025-08-13	Wu Xiaobin	Option exercise	23K	$174.43
2025-08-13	Wu Xiaobin	Option exercise	27K	$155.68
2025-08-13	Wu Xiaobin	Sell	8.9K	$300.33
2025-08-13	Wu Xiaobin	Sell	4.5K	$301.49
2025-08-13	Wu Xiaobin	Sell	5.8K	$302.45
2025-08-13	Wu Xiaobin	Sell	3.5K	$303.54
2025-08-13	Wu Xiaobin	Sell	528	$305.59
2025-08-13	Wu Xiaobin	Sell	9.6K	$306.74
2025-08-13	Wu Xiaobin	Sell	9.6K	$307.38
2025-08-13	Lee Chan Henry	Sell	1.1K	$300.00
2025-08-13	Lee Chan Henry	Option exercise	4.4K	$194.47
2025-08-13	Lee Chan Henry	Option exercise	3.8K	$159.03
2025-08-13	Lee Chan Henry	Sell	6.1K	$300.19
2025-08-13	Lee Chan Henry	Sell	3.8K	$301.00
2025-08-01	Rosenberg Aaron	Sell	1.2K	$290.47
2025-07-30	Lee Chan Henry	Sell	920	$304.60
2025-07-30	Wang Lai	Sell	259	$305.00
2025-07-29	Wang Lai	Sell	800	$304.16
2025-07-29	Wang Lai	Sell	2.9K	$302.00
2025-07-29	Wang Lai	Sell	292	$302.92
2025-07-18	Wang Lai	Sell	700	$300.00
2025-07-09	OYLER JOHN	Sell	9.3K	$253.18
2025-07-09	OYLER JOHN	Sell	1.6K	$254.83
2025-07-09	OYLER JOHN	Sell	10K	$254.10
2025-07-09	OYLER JOHN	Sell	6.7K	$252.23
2025-06-24	Wang Xiaodong	Sell	300	$263.50
2025-06-24	Wang Xiaodong	Sell	1.1K	$265.35
2025-06-24	Wang Xiaodong	Sell	507	$266.57
2025-06-24	Wang Xiaodong	Sell	100	$267.81
2025-06-23	OYLER JOHN	Sell	100	$262.90
2025-06-23	OYLER JOHN	Sell	3.1K	$261.57
2025-06-23	Wu Xiaobin	Sell	1.4K	$260.00
2025-06-23	Wang Lai	Sell	1.0K	$260.00
2025-06-17	Wang Lai	Sell	470	$251.37
2025-06-17	OYLER JOHN	Sell	1.5K	$256.49
2025-06-17	Wu Xiaobin	Sell	630	$250.87
2025-06-16	Wu Xiaobin	Sell	1.4K	$265.47
2025-06-16	Lee Chan Henry	Sell	422	$266.50
2025-06-16	Wang Lai	Sell	1.2K	$266.40
2025-06-16	Wu Xiaobin	Sell	100	$266.22
2025-06-16	OYLER JOHN	Sell	3.7K	$266.05
2025-06-11	Ball Titus B.	Sell	134	$258.36
2025-06-10	Lee Chan Henry	Grant	47K	—
2025-06-10	Rosenberg Aaron	Grant	64K	—
2025-06-10	Wang Lai	Grant	86K	—
2025-06-10	Wu Xiaobin	Grant	123K	—
2025-06-10	Wang Xiaodong	Grant	99K	—
2025-06-10	Wang Xiaodong	Option exercise	42K	$6.50
2025-06-10	Wang Xiaodong	Sell	2.9K	$261.20
2025-06-10	Wang Xiaodong	Sell	16K	$262.20
2025-06-10	Wang Xiaodong	Sell	16K	$263.17
2025-06-10	Wang Xiaodong	Sell	6.8K	$264.08
2025-06-10	Wang Xiaodong	Sell	100	$264.85
2025-06-10	OYLER JOHN	Grant	185K	—
2025-06-10	Ball Titus B.	Grant	30K	—
2025-06-10	Yi Qingqing	Other	30K	—
2025-06-06	OYLER JOHN	Sell	1.4K	$250.84
2025-06-06	Lee Chan Henry	Sell	470	$255.78
2025-06-06	Lee Chan Henry	Sell	230	$256.79
2025-06-06	Wang Lai	Sell	600	$250.71
2025-06-06	Wang Lai	Sell	202	$251.89
2025-06-06	Wang Lai	Sell	300	$253.19
2025-06-06	Wang Lai	Sell	300	$255.30
2025-06-06	Wu Xiaobin	Sell	400	$250.74
2025-06-06	Wu Xiaobin	Sell	500	$251.85
2025-06-06	Wu Xiaobin	Sell	400	$253.50
2025-06-06	Wu Xiaobin	Sell	400	$255.31
2025-06-06	Wu Xiaobin	Sell	234	$255.77
2025-06-06	OYLER JOHN	Sell	1.4K	$251.88
2025-06-06	OYLER JOHN	Sell	1.0K	$253.49
2025-06-06	OYLER JOHN	Sell	927	$254.97
2025-06-06	OYLER JOHN	Sell	400	$255.74
2025-05-21	Yi Qingqing	Grant	11K	—
2025-05-21	Sharp Shalini	Grant	11K	—
2025-05-21	BRANDICOURT OLIVIER	Grant	11K	—
2025-05-21	Riva Alessandro	Grant	11K	—
2025-05-21	Dugan Margaret	Grant	11K	—
2025-05-21	Sanders Corazon (Corsee) D.	Grant	11K	—
2025-05-21	HOOPER ANTHONY C	Grant	11K	—
2025-05-21	BAKER BROS. ADVISORS LP	Grant	22K	—
2025-05-21	BAKER BROS. ADVISORS LP	Grant	22K	—
2025-05-13	Wang Xiaodong	Option exercise	42K	$6.50
2025-05-13	Wang Xiaodong	Sell	10K	$222.83
2025-05-13	Wang Xiaodong	Sell	21K	$223.41
2025-05-13	Wang Xiaodong	Sell	10K	$224.32
2025-05-13	Wang Xiaodong	Sell	200	$225.68
2025-05-09	OYLER JOHN	Option exercise	4.1M	$0.50
2025-05-09	OYLER JOHN	Tax withheld	2.0M	$17.85
2025-04-14	Wang Xiaodong	Option exercise	42K	$6.50
2025-04-14	Wang Xiaodong	Sell	995	$237.56
2025-04-14	Wang Xiaodong	Sell	805	$238.48
2025-04-14	Wang Xiaodong	Sell	2.9K	$239.51
2025-04-14	Wang Xiaodong	Sell	5.5K	$240.41
2025-04-14	Wang Xiaodong	Sell	2.2K	$241.51
2025-04-14	Wang Xiaodong	Sell	15K	$242.59
2025-04-14	Wang Xiaodong	Sell	6.4K	$243.41
2025-04-14	Wang Xiaodong	Sell	1.6K	$244.56
2025-04-14	Wang Xiaodong	Sell	2.1K	$245.56
2025-04-14	Wang Xiaodong	Sell	1.9K	$246.40
2025-04-14	Wang Xiaodong	Sell	1.5K	$247.46
2025-04-14	Wang Xiaodong	Sell	535	$248.90
2025-04-14	Wang Xiaodong	Sell	365	$249.45
2025-04-01	Wu Xiaobin	Option exercise	16K	$119.96
2025-04-01	Wu Xiaobin	Option exercise	35K	$174.43
2025-04-01	Wu Xiaobin	Sell	28K	$280.31
2025-04-01	Wu Xiaobin	Sell	6.4K	$281.67
2025-04-01	Wu Xiaobin	Sell	12K	$282.76
2025-04-01	Wu Xiaobin	Sell	5.1K	$283.79
2025-03-18	Wang Xiaodong	Option exercise	42K	$6.50
2025-03-18	Wang Xiaodong	Sell	2.4K	$258.25
2025-03-18	Wang Xiaodong	Sell	6.9K	$259.08
2025-03-18	Wang Xiaodong	Sell	2.7K	$259.86
2025-03-18	Wang Xiaodong	Sell	10K	$261.44
2025-03-18	Wang Xiaodong	Sell	11K	$262.12
2025-03-18	Wang Xiaodong	Sell	6.9K	$263.08
2025-03-18	Wang Xiaodong	Sell	1.1K	$264.01
2025-03-14	Wu Xiaobin	Sell	0	—
2025-03-11	Wang Xiaodong	Gift	159K	—
2025-03-10	OYLER JOHN	Sell	7.1K	$241.92
2025-03-10	OYLER JOHN	Sell	9.3K	$243.04
2025-03-10	OYLER JOHN	Sell	5.3K	$244.04
2025-03-10	OYLER JOHN	Option exercise	41K	$6.50
2025-03-10	OYLER JOHN	Sell	3.0K	$245.19
2025-03-10	OYLER JOHN	Sell	4.9K	$246.11
2025-03-10	OYLER JOHN	Sell	700	$246.85
2025-03-10	OYLER JOHN	Sell	1.9K	$238.74
2025-03-10	OYLER JOHN	Sell	6.8K	$239.59
2025-03-10	OYLER JOHN	Option exercise	498K	$0.50
2025-03-10	OYLER JOHN	Sell	2.2K	$240.70
2025-03-07	OYLER JOHN	Sell	1.1K	$253.21
2025-03-07	OYLER JOHN	Sell	1.3K	$254.10
2025-03-07	OYLER JOHN	Sell	2.4K	$255.02
2025-03-07	OYLER JOHN	Sell	500	$256.10
2025-03-07	OYLER JOHN	Sell	8.9K	$249.04
2025-03-07	OYLER JOHN	Option exercise	709K	$0.50
2025-03-07	OYLER JOHN	Option exercise	59K	$6.50
2025-03-07	OYLER JOHN	Sell	1.4K	$246.03
2025-03-07	OYLER JOHN	Sell	2.1K	$246.09
2025-03-07	OYLER JOHN	Sell	1.2K	$246.69
2025-03-07	OYLER JOHN	Sell	14K	$246.91
2025-03-07	OYLER JOHN	Sell	7.6K	$247.99
2025-03-07	OYLER JOHN	Sell	13K	$249.97
2025-03-07	OYLER JOHN	Sell	2.3K	$251.00
2025-03-07	OYLER JOHN	Sell	3.3K	$252.24
2025-03-06	OYLER JOHN	Option exercise	486K	$0.50
2025-03-06	OYLER JOHN	Option exercise	40K	$6.50
2025-03-06	OYLER JOHN	Sell	3.5K	$256.91
2025-03-06	OYLER JOHN	Sell	14K	$257.92
2025-03-06	OYLER JOHN	Sell	8.2K	$258.91
2025-03-06	OYLER JOHN	Sell	6.7K	$259.77
2025-03-06	OYLER JOHN	Sell	2.9K	$261.08
2025-03-06	OYLER JOHN	Sell	3.4K	$262.03
2025-03-06	OYLER JOHN	Sell	1.7K	$262.97
2025-03-06	OYLER JOHN	Sell	100	$264.27
2025-03-05	OYLER JOHN	Grant	201K	—
2025-03-05	Rosenberg Aaron	Grant	49K	—
2025-03-05	Wu Xiaobin	Grant	104K	—
2025-03-05	Wu Xiaobin	Option exercise	7.0K	$169.65
2025-03-05	Wu Xiaobin	Option exercise	45K	$119.96
2025-03-05	Wu Xiaobin	Sell	18K	$260.39
2025-03-05	Wu Xiaobin	Sell	11K	$261.61
2025-03-05	Wu Xiaobin	Sell	23K	$262.51
2025-03-05	Wu Xiaobin	Sell	200	$263.00
2025-03-05	Wang Lai	Grant	69K	—
2025-03-05	Lee Chan Henry	Grant	40K	—
2025-03-04	Wang Xiaodong	Sell	1.3K	$254.77
2025-03-04	Wang Xiaodong	Sell	700	$251.70
2025-03-04	Wang Xiaodong	Sell	2.0K	$252.72
2025-03-04	Wang Xiaodong	Sell	825	$253.55
2025-03-04	Wang Xiaodong	Sell	1.2K	$255.71
2025-03-04	Wang Xiaodong	Sell	1.8K	$256.83
2025-03-04	Wang Xiaodong	Sell	323	$257.41
2025-03-03	OYLER JOHN	Option exercise	1.2M	$0.50
2025-03-03	OYLER JOHN	Option exercise	101K	$6.50
2025-03-03	OYLER JOHN	Sell	6.0K	$240.53
2025-03-03	OYLER JOHN	Sell	14K	$241.38
2025-03-03	OYLER JOHN	Sell	8.2K	$242.46
2025-03-03	OYLER JOHN	Sell	11K	$243.44
2025-03-03	OYLER JOHN	Sell	4.9K	$244.45
2025-03-03	OYLER JOHN	Sell	18K	$244.56
2025-03-03	OYLER JOHN	Sell	1.1K	$245.36
2025-03-03	OYLER JOHN	Sell	19K	$245.51
2025-03-03	OYLER JOHN	Sell	7.2K	$246.57
2025-03-03	OYLER JOHN	Sell	6.5K	$247.63
2025-03-03	OYLER JOHN	Sell	3.9K	$248.63
2025-03-03	OYLER JOHN	Sell	600	$249.25
2025-02-28	Wu Xiaobin	Sell	0	—
2025-02-28	BAKER BROS. ADVISORS LP	Sell	61K	$260.00
2025-02-28	BAKER BROS. ADVISORS LP	Sell	672K	$260.00
2025-02-27	Lee Chan Henry	Sell	1.2K	$275.00
2025-02-21	Wang Lai	Sell	1.3K	$254.82
2025-02-21	Wang Lai	Sell	575	$255.86
2025-02-21	Wang Lai	Sell	479	$256.70
2025-02-21	Wang Lai	Sell	437	$258.18
2025-02-21	Wang Lai	Sell	1.8K	$258.73
2025-02-21	Wang Lai	Sell	400	$260.17
2025-02-21	Lee Chan Henry	Sell	504	$256.84
2025-02-21	Lee Chan Henry	Sell	598	$258.69
2025-02-21	Lee Chan Henry	Sell	100	$260.21
2025-02-20	Wu Xiaobin	Option exercise	21K	$169.65
2025-02-20	Wu Xiaobin	Sell	21K	$240.07
2025-02-18	Wu Xiaobin	Sell	7.9K	$241.26
2025-02-18	Wu Xiaobin	Sell	3.2K	$242.08
2025-02-18	Wu Xiaobin	Option exercise	31K	$169.65
2025-02-18	Wu Xiaobin	Sell	20K	$240.31
2025-02-04	Wang Xiaodong	Sell	1.4K	$228.04
2025-02-04	Wang Xiaodong	Sell	2.2K	$225.27
2025-02-04	Wang Xiaodong	Option exercise	42K	$6.50
2025-02-04	Wang Xiaodong	Sell	9.1K	$223.00
2025-02-04	Wang Xiaodong	Sell	1.5K	$224.18
2025-02-04	Wang Xiaodong	Sell	18K	$226.35
2025-02-04	Wang Xiaodong	Sell	9.8K	$227.00
2025-01-07	Wang Xiaodong	Option exercise	42K	$6.50
2025-01-07	Wang Xiaodong	Sell	19K	$175.46
2025-01-07	Wang Xiaodong	Sell	11K	$176.67
2025-01-07	Wang Xiaodong	Sell	4.3K	$177.42
2025-01-07	Wang Xiaodong	Sell	5.6K	$178.39
2025-01-07	Wang Xiaodong	Sell	1.3K	$179.18

All non-derivative Form 4 activity (SEC), newest first.

Notable events (8-K)

Date	Items
2026-06-26	Other	filing ↗
2026-06-11	Exec/director changeShareholder voteExhibits	filing ↗
2026-05-15	OtherExhibits	filing ↗
2026-05-06	ResultsExhibits	filing ↗
2026-04-14	ResultsExhibits	filing ↗
2026-02-26	ResultsExhibits	filing ↗
2025-12-19	1.02	filing ↗
2025-12-18	Exec/director change	filing ↗

Recent filings

Form	Filed	Period	Accession
8-K	2026-06-26	2026-06-26	0001651308-26-000020 ↗
8-K	2026-06-11	2026-06-11	0001651308-26-000017 ↗
8-K	2026-05-15	2026-05-13	0001651308-26-000012 ↗
8-K	2026-05-06	2026-05-06	0001628280-26-030866 ↗
10-Q	2026-05-06	2026-03-31	0001628280-26-030867 ↗
8-K	2026-04-14	2026-04-14	0001651308-26-000008 ↗
10-K	2026-02-26	2025-12-31	0001628280-26-011946 ↗
8-K	2026-02-26	2026-02-26	0001628280-26-011941 ↗
8-K	2025-12-19	2025-12-16	0001651308-25-000153 ↗
8-K	2025-12-18	2025-12-17	0001651308-25-000151 ↗
8-K	2025-11-19	2025-11-13	0001651308-25-000148 ↗
10-Q	2025-11-06	2025-09-30	0001628280-25-049824 ↗