Dianthus Therapeutics, Inc. /DE/
DNTH · Pharmaceutical Preparations · 54.7M shares · -7%/yr ↓ buyback · EDGAR filings ↗
Reference price $80.34 · est. market cap ~$4.4B — last insider sale, 2026-06-17 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)
Grade
D46Clinical/early-stage biotech — complement/autoimmune clinical, very well-funded.
Strengths
- Liquidity — current ratio 13.3 (87th)
Risks
- Pre-revenue, deep losses — per metrics
- Pre-revenue/clinical-stage — history of losses & need for capital per risk factors
- Binary clinical & funding risk — per 10-K
Notable findings
- Fund exitedNotable fund(s) exited this quarter: VANGUARD GROUP INC, RENAISSANCE TECHNOLOGIES LLC
- Net lossNet loss (net margin -7973.3%)
- Strong balance sheetStrong balance sheet — $160M cash & investments
- Buying back stockNet buyback — share count -7%/yr over 4y
- AccumulatingInstitutional holders rose 10→11 QoQ (2025-12-31→2026-03-31)
- Revenue declineRevenue -28.3% YoY
- Insider sellingInsider selling — 28 open-market sale(s) by 6 insider(s) (cluster of 6 insiders, ~$34M, last 6mo) Form 4 ↗
- Notable holderHeld by 4 notable fund(s): FMR LLC, CITADEL ADVISORS LLC, STATE STREET CORP +1 more (as of 2026-03-31)
Quarterly revenue
Last 4 quarters · from SEC filings.
Key metrics
Operating margin
-8739.3%
Net margin
-7973.3%
Return on equity
-32.9%
Return on assets
-30.6%
Revenue growth (QoQ)
-28.3%
Current ratio
13.3×
Tangible book value
$493M
Cash & investments
$160M
Stock comp / revenue
1119.5%
Insider transactions · last 18 months
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| 2026-06-17 | Veness Adam M | Sell | 13K | $81.38 |
| 2026-06-17 | Veness Adam M | Option exercise | 30K | $17.88 |
| 2026-06-17 | Veness Adam M | Sell | 17K | $80.34 |
| 2026-06-01 | Randhawa Simrat | Option exercise | 6.2K | $21.77 |
| 2026-06-01 | Randhawa Simrat | Option exercise | 9.4K | $22.07 |
| 2026-06-01 | Randhawa Simrat | Sell | 5.4K | $89.72 |
| 2026-06-01 | Randhawa Simrat | Sell | 4.2K | $91.37 |
| 2026-06-01 | Randhawa Simrat | Sell | 17K | $90.72 |
| 2026-06-01 | Randhawa Simrat | Option exercise | 4.0K | $8.44 |
| 2026-06-01 | Randhawa Simrat | Option exercise | 6.9K | $17.88 |
| 2026-05-08 | Soteropoulos Paula | Option exercise | 599 | $8.44 |
| 2026-05-08 | Soteropoulos Paula | Sell | 599 | $85.47 |
| 2026-04-09 | Savitz Ryan | Option exercise | 8.2K | $17.88 |
| 2026-04-09 | Savitz Ryan | Sell | 8.2K | $89.84 |
| 2026-03-31 | Savitz Ryan | Option exercise | 40K | $17.88 |
| 2026-03-31 | Savitz Ryan | Option exercise | 74K | $8.44 |
| 2026-03-31 | Savitz Ryan | Sell | 1.4K | $78.33 |
| 2026-03-31 | Savitz Ryan | Sell | 22K | $78.86 |
| 2026-03-31 | Savitz Ryan | Sell | 1.5K | $80.25 |
| 2026-03-31 | Savitz Ryan | Sell | 800 | $81.36 |
| 2026-03-31 | Savitz Ryan | Sell | 2.4K | $82.84 |
| 2026-03-31 | Savitz Ryan | Sell | 60K | $83.90 |
| 2026-03-31 | Savitz Ryan | Sell | 19K | $84.57 |
| 2026-03-31 | Savitz Ryan | Sell | 7.2K | $85.54 |
| 2026-03-31 | Soteropoulos Paula | Option exercise | 599 | $8.44 |
| 2026-03-31 | Soteropoulos Paula | Sell | 599 | $80.11 |
| 2026-03-24 | Soteropoulos Paula | Option exercise | 28K | $8.44 |
| 2026-03-24 | Soteropoulos Paula | Sell | 28K | $78.05 |
| 2026-03-16 | Garcia Marino | Option exercise | 60K | $6.70 |
| 2026-03-16 | Garcia Marino | Option exercise | 5.6K | $17.88 |
| 2026-03-12 | Garcia Marino | Sell | 13K | $82.60 |
| 2026-03-12 | Randhawa Simrat | Option exercise | 8.0K | $8.44 |
| 2026-03-12 | Randhawa Simrat | Option exercise | 5.0K | $17.88 |
| 2026-03-12 | Randhawa Simrat | Option exercise | 8.3K | $21.77 |
| 2026-03-12 | Randhawa Simrat | Option exercise | 12K | $22.07 |
| 2026-03-12 | Randhawa Simrat | Sell | 34K | $81.48 |
| 2026-03-12 | Garcia Marino | Option exercise | 123K | $6.70 |
| 2026-03-12 | Garcia Marino | Sell | 44K | $80.69 |
| 2026-03-12 | Garcia Marino | Sell | 66K | $81.74 |
| 2026-03-12 | Garcia Marino | Sell | 200 | $83.38 |
| 2026-03-12 | Garcia Marino | Sell | 900 | $85.53 |
| 2026-03-12 | CARR EDWARD | Option exercise | 16K | $17.88 |
| 2026-03-12 | CARR EDWARD | Option exercise | 18K | $22.07 |
| 2026-03-12 | CARR EDWARD | Option exercise | 10K | $21.77 |
| 2026-03-12 | CARR EDWARD | Sell | 16K | $80.71 |
| 2026-03-12 | CARR EDWARD | Sell | 23K | $81.75 |
| 2026-03-12 | CARR EDWARD | Sell | 3.9K | $82.66 |
| 2026-03-12 | CARR EDWARD | Sell | 200 | $83.38 |
| 2026-03-12 | CARR EDWARD | Sell | 300 | $85.53 |
| 2025-12-04 | Savitz Ryan | Option exercise | 20K | $8.44 |
| 2025-12-04 | Savitz Ryan | Sell | 20K | $45.18 |
| 2025-11-14 | Randhawa Simrat | Option exercise | 40K | $17.88 |
| 2025-11-14 | Randhawa Simrat | Option exercise | 37K | $21.77 |
| 2025-11-14 | Randhawa Simrat | Option exercise | 31K | $22.07 |
| 2025-11-14 | Randhawa Simrat | Sell | 109K | $38.14 |
| 2025-11-13 | Randhawa Simrat | Sell | 19K | $37.72 |
| 2025-11-13 | Randhawa Simrat | Option exercise | 84K | $8.44 |
| 2025-11-13 | Randhawa Simrat | Option exercise | 3.5K | $17.88 |
| 2025-11-13 | Randhawa Simrat | Sell | 26K | $35.80 |
| 2025-11-13 | Randhawa Simrat | Sell | 43K | $37.04 |
| 2025-09-09 | Savitz Ryan | Option exercise | 20K | $8.44 |
| 2025-09-09 | Savitz Ryan | Sell | 20K | $35.00 |
All non-derivative Form 4 activity (SEC), newest first.
Notable events (8-K)
Recent filings
| Form | Filed | Period | Accession |
|---|---|---|---|
| 8-K | 2026-06-12 | 2026-06-12 | 0001690585-26-000029 ↗ |
| 8-K | 2026-05-22 | 2026-05-21 | 0001690585-26-000026 ↗ |
| 8-K | 2026-05-05 | 2026-05-05 | 0001690585-26-000021 ↗ |
| 10-Q | 2026-05-05 | 2026-03-31 | 0001690585-26-000022 ↗ |
| 8-K | 2026-03-26 | 2026-03-26 | 0001690585-26-000010 ↗ |
| 8-K | 2026-03-12 | 2026-03-10 | 0001193125-26-103053 ↗ |
| 10-K | 2026-03-09 | 2025-12-31 | 0001690585-26-000006 ↗ |
| 8-K | 2026-03-09 | 2026-03-09 | 0001193125-26-097555 ↗ |
| 8-K | 2026-01-12 | 2026-01-12 | 0001193125-26-009898 ↗ |
| 10-Q | 2025-11-05 | 2025-09-30 | 0001193125-25-266920 ↗ |
| 8-K | 2025-11-05 | 2025-11-05 | 0001193125-25-266867 ↗ |
| 8-K | 2025-11-03 | 2025-11-03 | 0001193125-25-262188 ↗ |