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BICYCLE THERAPEUTICS PLC

BCYC · Pharmaceutical Preparations · 30.0M shares · +34%/yr ↑ dilution · EDGAR filings ↗

Reference price $5.05 · est. market cap ~$152M — last insider sale, 2026-04-06 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)

Grade

D46

Clinical/early-stage biotech — bicyclic-peptide oncology clinical, heavy burn ($252M), very well-funded.

Strengths

Risks

Notable findings

Quarterly revenue

2025-06-30 · $3M2025-09-30 · $12M2025-12-31 · $48M2026-03-31 · $887K

Last 4 quarters · from SEC filings.

Key metrics

Operating margin
-340.4%
Net margin
-301.7%
Return on equity
-35.9%
Return on assets
-30.5%
Revenue growth (QoQ)
-98.2%
Current ratio
12.0×
Free cash flow
-$252M
EBITDA
-$241M
Tangible book value
$610M
Cash & investments
$628M
Cash runway
10q
Stock comp / revenue
54.4%

Insider transactions · last 18 months

DateInsiderTypeSharesPrice
2026-04-06Lee KevinSell1.7K$5.05
2026-04-06Skynner MichaelSell525$5.05
2026-04-06Hannay Michael Charles FergusonSell251$5.05
2026-04-06Thompson Travis AlvinSell102$5.05
2026-04-06Perry Jennifer ScottSell37$5.05
2026-04-06Perry Jennifer ScottSell333$5.04
2026-04-02Thompson Travis AlvinSell799$4.91
2026-04-02Lee KevinSell6.0K$4.91
2026-04-02Hannay Michael Charles FergusonSell1.5K$4.91
2026-04-02Skynner MichaelSell1.9K$4.91
2026-04-02Perry Jennifer ScottSell1.0K$4.91
2026-01-05Young AlethiaSell1.9K$6.54
2026-01-05Milnes AlistairSell3.4K$6.46
2026-01-05Hannay Michael Charles FergusonSell2.4K$6.45
2026-01-05Lee KevinSell11K$6.46
2026-01-05Skynner MichaelSell3.3K$6.46
2026-01-05Thompson Travis AlvinSell1.1K$6.45
2026-01-05Young AlethiaSell2.5K$6.45
2026-01-02Gutierrez-Ramos Jose-CarlosGrant9.5K
2026-01-02Hoppenot HerveGrant3.0K
2026-01-02BAKER BROS. ADVISORS LPGrant19K
2026-01-02BAKER BROS. ADVISORS LPGrant19K
2026-01-02Skynner MichaelSell3.0K$6.80
2026-01-02Swanton Robert CharlesGrant3.7K
2026-01-02Hannay Michael Charles FergusonGrant50K
2026-01-02Hannay Michael Charles FergusonSell2.8K$6.80
2026-01-02Thompson Travis AlvinGrant38K
2026-01-02Thompson Travis AlvinSell1.3K$6.80
2026-01-02Young AlethiaGrant50K
2026-01-02Young AlethiaSell3.3K$6.80
2026-01-02Sands Stephen H.Grant9.5K
2026-01-02Milnes AlistairGrant50K
2026-01-02Milnes AlistairSell3.2K$6.80
2026-01-02Riva AlessandroGrant7.4K
2026-01-02Bourque JaniceGrant9.5K
2026-01-02Winter Gregory PaulGrant9.5K
2026-01-02Lee KevinGrant165K
2026-01-02Lee KevinSell10K$6.80
2026-01-02Skynner MichaelGrant50K
2026-01-02DANSEY ROGER DGrant3.0K
2025-10-03Milnes AlistairSell978$8.41
2025-10-03Thompson Travis AlvinSell103$8.41
2025-10-03Lee KevinSell3.2K$8.41
2025-10-03Hannay Michael Charles FergusonSell250$8.41
2025-10-03Skynner MichaelSell978$8.41
2025-10-02Milnes AlistairSell1.1K$8.40
2025-10-02Lee KevinSell2.3K$8.40
2025-10-02Skynner MichaelSell824$8.40
2025-10-02Swanton Robert CharlesSell102$8.55
2025-10-02Hannay Michael Charles FergusonSell473$8.40
2025-10-02Thompson Travis AlvinSell221$8.40
2025-10-02Young AlethiaSell217$8.40
2025-10-02Young AlethiaSell265$8.61
2025-09-08Hoppenot HerveGrant12K
2025-09-08DANSEY ROGER DGrant12K
2025-08-12Swanton Robert CharlesGrant12K
2025-07-03Skynner MichaelSell966$7.44
2025-07-03Lee KevinSell3.2K$7.44
2025-07-03Hannay Michael Charles FergusonSell248$7.44
2025-07-03Thompson Travis AlvinSell100$7.44
2025-07-03Milnes AlistairSell966$7.44
2025-07-02Thompson Travis AlvinSell206$7.09
2025-07-02Milnes AlistairSell1.1K$7.09
2025-07-02Hannay Michael Charles FergusonSell474$7.09
2025-07-02Young AlethiaSell204$7.09
2025-07-02Lee KevinSell2.3K$7.09
2025-07-02Skynner MichaelSell825$7.09
2025-04-03Lee KevinSell3.4K$7.48
2025-04-03Milnes AlistairSell1.0K$7.48
2025-04-03Thompson Travis AlvinSell109$7.48
2025-04-03Hannay Michael Charles FergusonSell266$7.48
2025-04-03Skynner MichaelSell1.0K$7.48
2025-04-02Young AlethiaSell215$8.02
2025-04-02Skynner MichaelSell814$8.02
2025-04-02Lee KevinSell2.2K$8.02
2025-04-02Milnes AlistairSell1.1K$8.02
2025-04-02Hannay Michael Charles FergusonSell467$8.02
2025-04-02Thompson Travis AlvinSell210$8.02
2025-03-25Riva AlessandroGrant12K
2025-01-06Thompson Travis AlvinSell2.7K$15.00
2025-01-03Thompson Travis AlvinSell159$14.75
2025-01-03Hannay Michael Charles FergusonSell239$14.75
2025-01-03Crockett NigelSell936$14.75
2025-01-03Skynner MichaelSell936$14.75
2025-01-03Lee KevinSell3.1K$14.75
2025-01-03Milnes AlistairSell936$14.75
2025-01-02Arroyo SantiagoSell4.9K$14.09
2025-01-02Crockett NigelGrant8.8K
2025-01-02Crockett NigelSell2.6K$14.09
2025-01-02Milnes AlistairGrant35K
2025-01-02Milnes AlistairSell4.6K$14.09
2025-01-02Skynner MichaelGrant35K
2025-01-02Skynner MichaelSell3.3K$14.09
2025-01-02Hannay Michael Charles FergusonGrant35K
2025-01-02Hannay Michael Charles FergusonSell1.9K$14.09
2025-01-02Lee KevinGrant123K
2025-01-02Lee KevinSell9.0K$14.09
2025-01-02Winter Gregory PaulGrant6.2K
2025-01-02Sands Stephen H.Grant5.4K
2025-01-02Kender Richard NGrant6.2K
2025-01-02Gutierrez-Ramos Jose-CarlosGrant6.2K
2025-01-02Bourque JaniceGrant6.2K
2025-01-02BAKER BROS. ADVISORS LPGrant4.4K
2025-01-02Thompson Travis AlvinGrant18K
2025-01-02BAKER BROS. ADVISORS LPGrant4.4K
2025-01-02Thompson Travis AlvinSell1.8K$14.09
2025-01-02Legault PierreGrant12K
2025-01-02Young AlethiaGrant35K
2025-01-02Young AlethiaSell1.4K$14.09
2025-01-02Arroyo SantiagoGrant35K

All non-derivative Form 4 activity (SEC), newest first.

Notable events (8-K)

DateItems
2026-06-18Shareholder votefiling ↗
2026-05-21OtherExhibitsfiling ↗
2026-04-30ResultsExhibitsfiling ↗
2026-04-20OtherExhibitsfiling ↗
2026-03-17ResultsExec/director changeExhibitsfiling ↗
2026-02-03Exec/director changefiling ↗
2026-01-12OtherExhibitsfiling ↗
2025-10-30ResultsExhibitsfiling ↗

Recent filings

FormFiledPeriodAccession
8-K2026-06-182026-06-170001104659-26-075451 ↗
8-K2026-05-212026-05-210001104659-26-065231 ↗
10-Q2026-04-302026-03-310001104659-26-052117 ↗
8-K2026-04-302026-04-300001104659-26-052107 ↗
8-K2026-04-202026-04-200001104659-26-045198 ↗
8-K2026-03-172026-03-170001104659-26-028954 ↗
10-K2026-03-172025-12-310001104659-26-028971 ↗
8-K2026-02-032026-01-290001104659-26-009501 ↗
8-K2026-01-122026-01-120001104659-26-002706 ↗
8-K2025-10-302025-10-300001104659-25-104004 ↗
10-Q2025-10-302025-09-300001104659-25-104010 ↗
8-K2025-09-082025-09-080001104659-25-088238 ↗