Kymera Therapeutics, Inc.

KYMR · Biological Products, (No Diagnostic Substances) · 82.3M shares · +50%/yr ↑ dilution · EDGAR filings ↗

Reference price $113.70 · est. market cap ~$9.4B — last insider sale, 2026-06-25 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)

Grade

D46

Clinical/early-stage biotech — targeted-protein-degradation clinical, heavy burn ($234M), very well-funded.

Strengths

Liquidity — current ratio 10.5 (85th)

Risks

Pre-revenue, deep losses — per metrics
Pre-revenue/clinical-stage — history of losses & need for capital per risk factors
Binary clinical & funding risk — per 10-K

Notable findings

Exec changeRecent 8-K item 5.02 8-K ↗
Net lossNet loss (net margin -794.0%)
Cash burnNegative free cash flow (-234.3M)
Fund exitedNotable fund(s) exited this quarter: VANGUARD GROUP INC
Chronic dilutionShare count +50%/yr over 3y (dilution, book value/share -4%)
Strong balance sheetStrong balance sheet — $1.6B cash & investments, ~28 quarters of runway
Notable holderHeld by 4 notable fund(s): FMR LLC, STATE STREET CORP, GOLDMAN SACHS GROUP INC +1 more (as of 2026-03-31)
Trial resultTrial topline data reported — see 8-K for outcome 8-K ↗
Insider sellingInsider selling — 167 open-market sale(s) by 8 insider(s) (cluster of 8 insiders, ~$165M, last 6mo) Form 4 ↗
Revenue declineRevenue -16.7% YoY

Quarterly revenue

2025-06-30 · $11M2025-09-30 · $3M2025-12-31 · $3M2026-03-31 · $34M

Last 4 quarters · from SEC filings.

Key metrics

Gross margin

0.0%

Operating margin

-891.1%

Net margin

-794.0%

Return on equity

-19.7%

Return on assets

-17.9%

Revenue growth (QoQ)

-16.7%

Current ratio

10.5×

Free cash flow

-$234M

EBITDA

-$341M

Tangible book value

$1.6B

Cash & investments

$1.6B

Cash runway

28q

Stock comp / revenue

152.8%

Insider transactions · last 18 months

Date	Insider	Type	Shares	Price
2026-06-25	Goodman Noah	Sell	2.5K	$119.00
2026-06-25	Booth Bruce	Sell	11K	$123.62
2026-06-25	Booth Bruce	Sell	10K	$113.70
2026-06-25	Booth Bruce	Sell	112K	$120.66
2026-06-25	Booth Bruce	Sell	41K	$121.38
2026-06-25	Booth Bruce	Sell	37K	$119.71
2026-06-25	Booth Bruce	Sell	12K	$124.61
2026-06-25	Booth Bruce	Sell	3.7K	$125.82
2026-06-25	Booth Bruce	Sell	1.6K	$126.71
2026-06-25	Booth Bruce	Sell	25K	$127.37
2026-06-25	Booth Bruce	Sell	2.2K	$128.69
2026-06-25	Booth Bruce	Sell	337	$129.61
2026-06-25	Booth Bruce	Sell	5.1K	$119.71
2026-06-25	Booth Bruce	Sell	16K	$120.66
2026-06-25	Booth Bruce	Sell	5.7K	$121.38
2026-06-25	Booth Bruce	Sell	698	$122.67
2026-06-25	Booth Bruce	Sell	1.5K	$123.62
2026-06-25	Booth Bruce	Sell	1.6K	$124.61
2026-06-25	Booth Bruce	Sell	522	$125.82
2026-06-25	Booth Bruce	Sell	223	$126.71
2026-06-25	Booth Bruce	Sell	3.5K	$127.37
2026-06-25	Booth Bruce	Sell	305	$128.69
2026-06-25	Booth Bruce	Sell	46	$129.61
2026-06-25	Booth Bruce	Sell	11K	$116.53
2026-06-25	Booth Bruce	Sell	3.4K	$117.50
2026-06-25	Booth Bruce	Sell	2.6K	$118.60
2026-06-25	Goodman Noah	Option exercise	5.0K	$21.05
2026-06-25	Goodman Noah	Sell	2.5K	$109.00
2026-06-25	Booth Bruce	Sell	5.0K	$122.67
2026-06-25	Booth Bruce	Sell	10.0K	$107.30
2026-06-25	Booth Bruce	Sell	159	$108.02
2026-06-25	Booth Bruce	Sell	14K	$108.83
2026-06-25	Booth Bruce	Sell	1.9K	$110.30
2026-06-25	Booth Bruce	Sell	614	$110.79
2026-06-25	Booth Bruce	Sell	719	$111.89
2026-06-25	Booth Bruce	Sell	9.2K	$114.65
2026-06-25	Booth Bruce	Sell	58K	$115.57
2026-06-25	Booth Bruce	Sell	82K	$116.53
2026-06-25	Booth Bruce	Sell	24K	$117.50
2026-06-25	Booth Bruce	Sell	19K	$118.60
2026-06-25	Booth Bruce	Sell	1.4K	$107.30
2026-06-25	Booth Bruce	Sell	23	$108.02
2026-06-25	Booth Bruce	Sell	2.0K	$108.83
2026-06-25	Booth Bruce	Sell	265	$110.30
2026-06-25	Booth Bruce	Sell	86	$110.79
2026-06-25	Booth Bruce	Sell	100	$111.89
2026-06-25	Booth Bruce	Sell	1.4K	$113.70
2026-06-25	Booth Bruce	Sell	1.3K	$114.65
2026-06-25	Booth Bruce	Sell	8.4K	$115.57
2026-06-24	Booth Bruce	Sell	104K	$100.42
2026-06-24	Booth Bruce	Sell	15K	$100.42
2026-06-24	Booth Bruce	Sell	14K	$101.14
2026-06-24	Booth Bruce	Sell	2.0K	$101.14
2026-06-23	Booth Bruce	Sell	1.2K	$99.98
2026-06-23	Booth Bruce	Sell	173	$99.98
2026-06-22	Goodman Noah	Sell	2.5K	$99.00
2026-06-22	Booth Bruce	Sell	18K	$103.42
2026-06-22	Booth Bruce	Sell	9.6K	$104.38
2026-06-22	Booth Bruce	Sell	2.6K	$103.42
2026-06-22	Booth Bruce	Sell	1.3K	$104.38
2026-06-22	Booth Bruce	Sell	15K	$92.14
2026-06-22	Booth Bruce	Sell	2.0K	$94.48
2026-06-22	Booth Bruce	Sell	12K	$95.12
2026-06-22	Booth Bruce	Sell	21K	$96.24
2026-06-22	Booth Bruce	Sell	16K	$97.68
2026-06-22	Booth Bruce	Sell	26K	$98.58
2026-06-22	Booth Bruce	Sell	52K	$99.57
2026-06-22	Booth Bruce	Sell	56K	$100.17
2026-06-22	Booth Bruce	Sell	6.6K	$101.61
2026-06-22	Booth Bruce	Sell	9.0K	$102.48
2026-06-22	Booth Bruce	Sell	2.2K	$92.14
2026-06-22	Booth Bruce	Sell	286	$94.48
2026-06-22	Booth Bruce	Sell	1.6K	$95.12
2026-06-22	Booth Bruce	Sell	2.9K	$96.24
2026-06-22	Booth Bruce	Sell	2.2K	$97.68
2026-06-22	Booth Bruce	Sell	3.6K	$98.58
2026-06-22	Booth Bruce	Sell	7.3K	$99.57
2026-06-22	Booth Bruce	Sell	7.9K	$100.17
2026-06-22	Booth Bruce	Sell	918	$101.61
2026-06-22	Booth Bruce	Sell	1.3K	$102.48
2026-06-22	Goodman Noah	Option exercise	2.5K	$21.05
2026-06-18	Booth Bruce	Sell	5.7K	$92.16
2026-06-18	Booth Bruce	Sell	793	$92.16
2026-06-18	Booth Bruce	Sell	4.5K	$91.85
2026-06-18	Booth Bruce	Sell	8.8K	$90.48
2026-06-18	Booth Bruce	Sell	32K	$91.85
2026-06-18	Booth Bruce	Sell	63K	$90.48
2026-06-17	Booth Bruce	Sell	92K	$90.38
2026-06-17	Booth Bruce	Option exercise	12K	$20.00
2026-06-17	Booth Bruce	Sell	13K	$90.38
2026-06-17	Booth Bruce	Sell	12K	$89.98
2026-06-02	Jacobs Bruce N.	Option exercise	13K	$2.08
2026-05-27	Chadwick Jeremy G	Sell	3.7K	$81.50
2026-05-27	Chadwick Jeremy G	Sell	600	$82.08
2026-05-26	Chadwick Jeremy G	Sell	3.7K	$78.36
2026-05-26	Chadwick Jeremy G	Sell	324	$79.17
2026-05-26	Chadwick Jeremy G	Sell	3.8K	$79.39
2026-05-26	Chadwick Jeremy G	Sell	4.5K	$80.02
2026-05-26	Chadwick Jeremy G	Sell	551	$80.71
2026-05-19	Esposito Pamela	Option exercise	1.0K	$31.20
2026-05-18	Jacobs Bruce N.	Option exercise	15K	$2.08
2026-05-11	Ridloff Elena	Option exercise	3.0K	$31.20
2026-05-11	Ridloff Elena	Sell	3.0K	$87.00
2026-04-29	Mainolfi Nello	Sell	17K	$80.74
2026-04-29	Mainolfi Nello	Option exercise	30K	$2.08
2026-04-29	Mainolfi Nello	Sell	12K	$81.70
2026-04-29	Mainolfi Nello	Sell	936	$82.45
2026-04-22	Booth Bruce	Option exercise	5.6K	$14.18
2026-04-22	Booth Bruce	Option exercise	259	$20.00
2026-04-22	Booth Bruce	Sell	5.9K	$89.96
2026-04-22	Booth Bruce	Sell	88	$90.08
2026-04-22	Booth Bruce	Sell	12	$90.08
2026-04-22	Chadwick Jeremy G	Option exercise	100	$30.17
2026-04-22	Chadwick Jeremy G	Option exercise	200	$43.50
2026-04-22	Chadwick Jeremy G	Sell	300	$90.00
2026-04-15	Booth Bruce	Option exercise	2.2K	$14.18
2026-04-15	Booth Bruce	Sell	2.2K	$89.95
2026-04-15	Booth Bruce	Sell	2.8K	$90.10
2026-04-15	Booth Bruce	Sell	385	$90.10
2026-04-15	Chadwick Jeremy G	Option exercise	1.3K	$43.50
2026-04-15	Chadwick Jeremy G	Sell	1.3K	$90.00
2026-04-14	Goodman Noah	Sell	1.3K	$90.00
2026-04-14	Chadwick Jeremy G	Option exercise	4.5K	$30.17
2026-04-14	Booth Bruce	Sell	4.2K	$89.97
2026-04-14	Booth Bruce	Option exercise	4.2K	$14.18
2026-04-14	Chadwick Jeremy G	Option exercise	785	$43.50
2026-04-14	Chadwick Jeremy G	Sell	5.3K	$90.00
2026-04-10	Goodman Noah	Sell	2.0K	$87.35
2026-04-09	Goodman Noah	Option exercise	2.5K	$21.05
2026-04-09	Goodman Noah	Sell	3.1K	$86.62
2026-04-09	Goodman Noah	Sell	2.7K	$87.11
2026-04-09	Goodman Noah	Sell	2.5K	$89.00
2026-04-01	Chadwick Jeremy G	Sell	14K	$85.41
2026-04-01	Chadwick Jeremy G	Option exercise	15K	$29.64
2026-04-01	Ridloff Elena	Sell	3.4K	$85.19
2026-04-01	Ridloff Elena	Option exercise	4.6K	$14.18
2026-04-01	Ridloff Elena	Sell	1.2K	$86.05
2026-04-01	Chadwick Jeremy G	Sell	1.1K	$86.05
2026-03-31	Ridloff Elena	Sell	7.4K	$85.37
2026-03-31	Chadwick Jeremy G	Sell	7.6K	$85.38
2026-03-31	Chadwick Jeremy G	Option exercise	7.6K	$29.64
2026-03-31	Ridloff Elena	Option exercise	7.4K	$14.18
2026-03-25	Chadwick Jeremy G	Option exercise	25K	$29.64
2026-03-25	Chadwick Jeremy G	Sell	25K	$80.26
2026-03-23	Chadwick Jeremy G	Sell	1.2K	$80.05
2026-03-23	Chadwick Jeremy G	Option exercise	84K	$29.64
2026-03-23	Chadwick Jeremy G	Sell	23K	$76.73
2026-03-23	Chadwick Jeremy G	Sell	53K	$77.21
2026-03-23	Chadwick Jeremy G	Sell	8.2K	$78.40
2026-03-23	Chadwick Jeremy G	Sell	6.1K	$79.87
2026-03-20	Esposito Pamela	Option exercise	2.5K	$49.10
2026-03-20	Esposito Pamela	Sell	700	$77.71
2026-03-20	Esposito Pamela	Sell	600	$79.24
2026-03-20	Esposito Pamela	Sell	1.2K	$79.94
2026-03-11	Chadwick Jeremy G	Option exercise	20K	$43.50
2026-03-11	Chadwick Jeremy G	Sell	1.8K	$82.13
2026-03-11	Chadwick Jeremy G	Sell	13K	$83.10
2026-03-11	Chadwick Jeremy G	Sell	11K	$83.72
2026-03-04	Chadwick Jeremy G	Sell	2.0K	$85.04
2026-03-04	Chadwick Jeremy G	Sell	394	$84.00
2026-03-04	Chadwick Jeremy G	Sell	1.1K	$85.78
2026-03-04	Chadwick Jeremy G	Sell	358	$86.62
2026-03-04	Gollob Jared	Sell	492	$84.00
2026-03-04	Gollob Jared	Sell	2.5K	$85.04
2026-03-04	Gollob Jared	Sell	1.4K	$85.78
2026-03-04	Gollob Jared	Sell	447	$86.62
2026-03-04	Jacobs Bruce N.	Sell	492	$84.00
2026-03-04	Jacobs Bruce N.	Sell	2.5K	$85.04
2026-03-04	Jacobs Bruce N.	Sell	1.4K	$85.78
2026-03-04	Jacobs Bruce N.	Sell	447	$86.62
2026-03-02	Gollob Jared	Grant	18K	—
2026-03-02	Gollob Jared	Sell	1.5K	$87.75
2026-03-02	Gollob Jared	Sell	1.1K	$88.50
2026-03-02	Gollob Jared	Sell	3.0K	$89.66
2026-03-02	Jacobs Bruce N.	Grant	18K	—
2026-03-02	Jacobs Bruce N.	Sell	2.0K	$87.75
2026-03-02	Jacobs Bruce N.	Sell	1.4K	$88.50
2026-03-02	Jacobs Bruce N.	Sell	4.1K	$89.66
2026-03-02	Booth Bruce	Sell	10K	$90.13
2026-03-02	Adams Brian	Grant	4.1K	—
2026-03-02	Chadwick Jeremy G	Grant	13K	—
2026-03-02	Chadwick Jeremy G	Sell	549	$87.75
2026-03-02	Chadwick Jeremy G	Sell	383	$88.50
2026-03-02	Chadwick Jeremy G	Sell	1.1K	$89.66
2026-03-02	Booth Bruce	Sell	72K	$90.13
2026-03-02	Goodman Noah	Grant	9.2K	—
2026-02-25	Mainolfi Nello	Option exercise	30K	$2.08
2026-02-25	Mainolfi Nello	Sell	20K	$89.78
2026-02-25	Mainolfi Nello	Sell	5.4K	$90.39
2026-02-25	Mainolfi Nello	Sell	3.3K	$91.76
2026-02-25	Mainolfi Nello	Sell	1.5K	$92.81
2026-02-25	Mainolfi Nello	Sell	8	$93.49
2026-02-20	Esposito Pamela	Option exercise	2.5K	$49.10
2026-02-20	Esposito Pamela	Sell	1.9K	$87.06
2026-02-20	Esposito Pamela	Sell	600	$88.10
2026-01-20	Esposito Pamela	Option exercise	3.0K	$31.20
2026-01-20	Esposito Pamela	Option exercise	2.5K	$49.10
2026-01-20	Esposito Pamela	Sell	400	$66.68
2026-01-20	Esposito Pamela	Sell	4.9K	$67.99
2026-01-20	Esposito Pamela	Sell	200	$68.52
2026-01-05	Mainolfi Nello	Option exercise	3.1K	$32.07
2025-12-31	Mainolfi Nello	Option exercise	30K	$2.08
2025-12-31	Mainolfi Nello	Sell	24K	$77.95
2025-12-31	Mainolfi Nello	Sell	6.0K	$78.52
2025-12-17	Esposito Pamela	Option exercise	3.0K	$31.20
2025-12-17	Esposito Pamela	Sell	8.0K	$82.34
2025-12-17	Esposito Pamela	Option exercise	12K	$27.67
2025-12-17	Esposito Pamela	Sell	15K	$81.56
2025-12-17	Esposito Pamela	Option exercise	13K	$49.10
2025-12-17	Mainolfi Nello	Option exercise	2.6K	$38.53
2025-12-17	Esposito Pamela	Sell	4.1K	$83.45
2025-12-17	Esposito Pamela	Sell	1.0K	$84.07
2025-12-12	Booth Bruce	Sell	108	$91.04
2025-12-12	Booth Bruce	Sell	570	$91.04
2025-12-11	Booth Bruce	Sell	5.1K	$91.23
2025-12-11	Booth Bruce	Sell	976	$91.23
2025-12-11	BAKER BROS. ADVISORS LP	Buy	167K	$86.00
2025-12-11	BAKER BROS. ADVISORS LP	Buy	1.8M	$86.00
2025-12-10	Booth Bruce	Sell	2.0K	$90.14
2025-12-10	Booth Bruce	Sell	3.4K	$89.25
2025-12-10	Booth Bruce	Sell	9.1K	$92.41
2025-12-10	Booth Bruce	Sell	16K	$93.20
2025-12-10	Booth Bruce	Sell	11K	$90.14
2025-12-10	Booth Bruce	Sell	6.0K	$88.64
2025-12-10	Booth Bruce	Sell	18K	$89.25
2025-12-10	Booth Bruce	Sell	31K	$88.64
2025-12-10	Booth Bruce	Sell	86K	$93.20
2025-12-10	Booth Bruce	Sell	47K	$92.41
2025-12-08	Albers Jeffrey W.	Option exercise	5.0K	$14.18
2025-12-08	Albers Jeffrey W.	Sell	2.7K	$89.32
2025-12-08	Albers Jeffrey W.	Sell	2.3K	$90.30
2025-12-08	Mainolfi Nello	Option exercise	100K	$2.08
2025-12-08	Mainolfi Nello	Sell	100K	$89.17
2025-12-08	Gollob Jared	Option exercise	49K	$5.33
2025-12-08	Gollob Jared	Sell	14K	$87.37
2025-12-08	Gollob Jared	Sell	18K	$88.02
2025-12-08	Gollob Jared	Sell	3.9K	$89.43
2025-12-08	Gollob Jared	Sell	8.6K	$90.12
2025-12-08	Gollob Jared	Sell	3.3K	$91.46
2025-12-08	Gollob Jared	Sell	1.4K	$92.19
2025-10-29	Mainolfi Nello	Option exercise	30K	$2.08
2025-10-29	Mainolfi Nello	Sell	1.9K	$59.72
2025-10-29	Mainolfi Nello	Sell	25K	$61.02
2025-10-29	Mainolfi Nello	Sell	3.6K	$61.46
2025-10-15	Gollob Jared	Option exercise	29K	$1.31
2025-10-15	Gollob Jared	Option exercise	22K	$2.08
2025-10-15	Gollob Jared	Sell	29K	$60.37
2025-10-15	Gollob Jared	Sell	9.0K	$61.49
2025-10-15	Gollob Jared	Sell	15K	$62.72
2025-10-15	Gollob Jared	Sell	6.5K	$63.09
2025-10-13	Gollob Jared	Option exercise	800	$1.31
2025-10-13	Gollob Jared	Option exercise	673	$2.08
2025-10-13	Gollob Jared	Sell	3.1K	$60.00
2025-10-13	Albers Jeffrey W.	Option exercise	5.0K	$10.34
2025-10-13	Albers Jeffrey W.	Sell	5.0K	$59.19
2025-09-17	Jacobs Bruce N.	Sell	79K	$50.00
2025-09-17	Jacobs Bruce N.	Option exercise	79K	$2.08
2025-09-16	Mainolfi Nello	Sell	30K	$49.00
2025-09-16	Mainolfi Nello	Option exercise	30K	$2.08
2025-09-03	Adams Brian	Grant	52K	—
2025-06-30	BVF PARTNERS L P/IL	Buy	59K	$44.00
2025-06-30	BAKER BROS. ADVISORS LP	Buy	600K	$44.00
2025-06-30	BAKER BROS. ADVISORS LP	Buy	55K	$44.00
2025-06-30	BVF PARTNERS L P/IL	Buy	143K	$44.00
2025-06-30	BVF PARTNERS L P/IL	Buy	116K	$44.00
2025-06-11	Ridloff Elena	Option exercise	4.5K	$20.29
2025-06-11	Ridloff Elena	Sell	4.5K	$50.00
2025-06-03	Albers Jeffrey W.	Sell	6.3K	$49.00
2025-06-03	Esposito Pamela	Option exercise	5.0K	$29.55
2025-06-03	Esposito Pamela	Sell	5.0K	$49.04
2025-06-03	Ridloff Elena	Option exercise	12K	$27.67
2025-06-03	Ridloff Elena	Sell	7.2K	$45.50
2025-06-03	Ridloff Elena	Sell	4.8K	$47.00
2025-06-03	Mainolfi Nello	Option exercise	30K	$2.08
2025-06-03	Mainolfi Nello	Sell	30K	$49.00
2025-06-03	Albers Jeffrey W.	Option exercise	6.3K	$10.34
2025-05-23	Chadwick Jeremy G	Sell	2.6K	$29.30
2025-04-08	Goodman Noah	Grant	50K	—
2025-03-31	Jacobs Bruce N.	Option exercise	25K	$2.08
2025-03-03	Chiniara Ellen	Sell	408	$31.00
2025-03-03	Chadwick Jeremy G	Grant	25K	—
2025-03-03	Chadwick Jeremy G	Sell	1.1K	$30.33
2025-03-03	Chadwick Jeremy G	Sell	252	$31.00
2025-03-03	Jacobs Bruce N.	Sell	5.8K	$30.33
2025-03-03	Jacobs Bruce N.	Sell	1.3K	$31.00
2025-03-03	Gollob Jared	Grant	30K	—
2025-03-03	Gollob Jared	Sell	4.7K	$30.33
2025-03-03	Gollob Jared	Sell	1.0K	$31.00
2025-03-03	Jacobs Bruce N.	Grant	30K	—
2025-03-03	Chiniara Ellen	Grant	28K	—
2025-03-03	Chiniara Ellen	Sell	1.8K	$30.33
2025-01-10	Jacobs Bruce N.	Option exercise	10K	$2.08
2025-01-10	Mainolfi Nello	Option exercise	10K	$2.08
2025-01-06	Chiniara Ellen	Sell	3.1K	$41.75

All non-derivative Form 4 activity (SEC), newest first.

Clinical trials

Trial	Title	Phase	Status	Primary completion
NCT07323654 ↗	A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma Eosinophilic Asthma	PHASE2	Recruiting	2027-12-01
NCT07217015 ↗	A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis Atopic Dermatitis	PHASE2	Recruiting	2027-06-01
NCT07412288 ↗	First-in-human Study of Orally Administered KT-579 in Healthy Adult Participants Healthy Participants	PHASE1	Recruiting	2026-12-01
NCT06945458 ↗	Safety, PK, PD, and Clinical Activity of Orally Administered KT-621 in Adult Patients With Atopic Dermatitis (AD) Atopic Dermatitis	PHASE1	Completed	2025-11-10
NCT06673667 ↗	First-in-human Study of Orally Administered KT-621 in Healthy Adult Participants Healthy Participants Study	PHASE1	Completed	2025-04-23
NCT05225584 ↗	Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors Non Hodgkin Lymphoma (NHL), Peripheral T-cell Lymphoma (PTCL)	PHASE1	Completed	2025-03-03
NCT05775406 ↗	Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors Myeloid Malignancies, Acute Lymphocytic Leukemia	PHASE1	Completed	2024-12-18
NCT05233033 ↗	Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma	PHASE1	Completed	2023-07-28
NCT04772885 ↗	A Single and Multiple Ascending Dose Trial of KT-474 in Healthy Adult Volunteers and Patients With Atopic Dermatitis (AD) or Hidradenitis Suppurativa (HS) Healthy Volunteer, Atopic Dermatitis	PHASE1	Completed	2022-10-20
NCT04440410 ↗	Evaluation of Cutaneous and Circulating Inflammatory Biomarkers in Hidradenitis Suppurativa and Atopic Dermatitis Hidradenitis Suppurativa, Dermatitis, Atopic	—	Completed	2021-03-24

Source: ClinicalTrials.gov (U.S. NIH) · active studies first.

Notable events (8-K)

Date	Items
2026-06-25	Reg FDOtherExhibits	filing ↗
2026-06-24	Shareholder vote	filing ↗
2026-06-08	Exec/director change	filing ↗
2026-04-30	ResultsExhibits	filing ↗
2026-03-27	5.03Exhibits	filing ↗
2026-02-26	Material agreement1.02OtherExhibits	filing ↗
2026-02-26	ResultsExhibits	filing ↗
2026-01-13	ResultsReg FDExhibits	filing ↗

Recent filings

Form	Filed	Period	Accession
8-K	2026-06-25	2026-06-25	0001193125-26-281817 ↗
8-K	2026-06-24	2026-06-24	0001193125-26-281051 ↗
8-K	2026-06-08	2026-06-05	0001193125-26-261698 ↗
8-K	2026-04-30	2026-04-30	0001193125-26-193957 ↗
10-Q	2026-04-30	2026-03-31	0001193125-26-193967 ↗
8-K	2026-03-27	2026-03-25	0001193125-26-129170 ↗
8-K	2026-02-26	2026-02-26	0001193125-26-073561 ↗
10-K	2026-02-26	2025-12-31	0001193125-26-073395 ↗
8-K	2026-02-26	2026-02-26	0001193125-26-073386 ↗
8-K	2026-01-13	2026-01-13	0001193125-26-011104 ↗
8-K	2025-12-10	2025-12-08	0001193125-25-314422 ↗
8-K	2025-12-08	2025-12-08	0001193125-25-310670 ↗