Clene Inc.
CLNN · Pharmaceutical Preparations · 12.8M shares · +1%/yr ↑ shares · EDGAR filings ↗
Reference price $6.20 · est. market cap ~$79M — last insider sale, 2026-05-12 (estimated from the dated SEC Form 4 price × shares outstanding — not a live quote)
Grade
F36Clinical/early-stage biotech — near-insolvent.
Strengths
- Liquidity — current ratio 0.83 (13th)
Risks
- Pre-revenue, deep losses — per metrics
- Pre-revenue/clinical-stage — history of losses & need for capital per risk factors
- Binary clinical & funding risk — per 10-K
Notable findings
- Going concernThese conditions raise substantial doubt about the Company’s ability to continue as a going concern
- Exec changeRecent 8-K item 5.02 8-K ↗
- Cash burnNegative free cash flow (-18.6M)
- Weak liquidityCurrent ratio 0.83 (<1)
- Negative equityNegative book equity (debt/equity -1.01)
- Net lossNet loss (net margin -13086.5%)
- Fund exitedNotable fund(s) exited this quarter: VANGUARD GROUP INC, FMR LLC
- Insider buyingInsider buying — 1 open-market buy(s) by 1 insider(s) (~$216,664, last 6mo) Form 4 ↗
- Insider sellingInsider selling — 43 open-market sale(s) by 1 insider(s) (~$4M, last 6mo) Form 4 ↗
- Revenue declineRevenue -80.5% YoY
- Notable holderHeld by 1 notable fund(s): STATE STREET CORP (as of 2026-03-31)
Quarterly revenue
Last 4 quarters · from SEC filings.
Key metrics
Gross margin
78.5%
Operating margin
-11541.5%
Net margin
-13086.5%
Return on equity
148.8%
Return on assets
-144.4%
ROIC
-9399.8%
Revenue growth (QoQ)
-80.5%
Debt / equity
-1.0×
Current ratio
0.8×
Free cash flow
-$19M
Tangible book value
-$18M
Cash & investments
$5M
Cash runway
1q
Stock comp / revenue
3191.0%
Insider transactions · last 18 months
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| 2026-05-12 | Ugwumba Chidozie | Sell | 73K | $6.20 |
| 2026-05-11 | Ugwumba Chidozie | Sell | 22K | $6.75 |
| 2026-05-04 | Ugwumba Chidozie | Sell | 73K | $6.80 |
| 2026-05-01 | Ugwumba Chidozie | Sell | 5.8K | $6.01 |
| 2026-04-30 | Ugwumba Chidozie | Sell | 5.7K | $6.08 |
| 2026-04-29 | Ugwumba Chidozie | Sell | 12K | $5.63 |
| 2026-04-28 | Ugwumba Chidozie | Sell | 1.6K | $5.90 |
| 2026-04-21 | Ugwumba Chidozie | Sell | 61K | $6.14 |
| 2026-04-20 | Ugwumba Chidozie | Sell | 4.3K | $6.12 |
| 2026-04-17 | Ugwumba Chidozie | Sell | 25K | $6.43 |
| 2026-04-16 | Ugwumba Chidozie | Sell | 7.7K | $6.40 |
| 2026-04-15 | Ugwumba Chidozie | Sell | 6.4K | $6.48 |
| 2026-04-02 | Ugwumba Chidozie | Sell | 25K | $4.81 |
| 2026-04-01 | Ugwumba Chidozie | Sell | 4.3K | $4.97 |
| 2026-03-31 | Ugwumba Chidozie | Sell | 68K | $4.88 |
| 2026-03-30 | Ugwumba Chidozie | Sell | 16K | $5.10 |
| 2026-03-27 | Ugwumba Chidozie | Sell | 17K | $4.75 |
| 2026-03-26 | Ugwumba Chidozie | Sell | 5.3K | $5.40 |
| 2026-03-25 | Ugwumba Chidozie | Sell | 7.1K | $5.50 |
| 2026-03-24 | Ugwumba Chidozie | Sell | 5.5K | $5.78 |
| 2026-02-03 | Ugwumba Chidozie | Sell | 5.6K | $4.10 |
| 2026-02-02 | Ugwumba Chidozie | Sell | 3.8K | $4.04 |
| 2026-01-30 | Ugwumba Chidozie | Sell | 5.7K | $4.13 |
| 2026-01-29 | Ugwumba Chidozie | Sell | 15K | $4.32 |
| 2026-01-28 | Ugwumba Chidozie | Sell | 8.7K | $4.91 |
| 2026-01-27 | Ugwumba Chidozie | Sell | 4.1K | $5.08 |
| 2026-01-26 | Ugwumba Chidozie | Sell | 6.4K | $5.02 |
| 2026-01-23 | Ugwumba Chidozie | Sell | 5.6K | $5.27 |
| 2026-01-22 | Ugwumba Chidozie | Sell | 13K | $5.32 |
| 2026-01-21 | Ugwumba Chidozie | Sell | 12K | $5.05 |
| 2026-01-20 | Ugwumba Chidozie | Sell | 12K | $4.80 |
| 2026-01-16 | Ugwumba Chidozie | Sell | 7.9K | $5.13 |
| 2026-01-15 | Ugwumba Chidozie | Sell | 13K | $5.10 |
| 2026-01-14 | Ugwumba Chidozie | Sell | 20K | $5.12 |
| 2026-01-13 | Mosca Alison | Grant | 17K | $6.00 |
| 2026-01-13 | Ugwumba Chidozie | Sell | 26K | $4.89 |
| 2026-01-13 | MATLIN DAVID J | Buy | 33K | $6.50 |
| 2026-01-12 | Ugwumba Chidozie | Sell | 33K | $5.50 |
| 2026-01-09 | Ugwumba Chidozie | Sell | 9.1K | $6.27 |
| 2026-01-09 | Mosca Alison | Other | 57K | — |
| 2026-01-08 | Ugwumba Chidozie | Sell | 3.2K | $6.09 |
| 2026-01-07 | Ugwumba Chidozie | Sell | 3.9K | $6.29 |
| 2026-01-06 | Ugwumba Chidozie | Sell | 3.1K | $6.04 |
| 2026-01-05 | Ugwumba Chidozie | Sell | 5.9K | $5.87 |
| 2026-01-02 | Ugwumba Chidozie | Sell | 4.0K | $5.73 |
| 2025-12-31 | Ugwumba Chidozie | Sell | 13K | $5.81 |
| 2025-12-30 | Ugwumba Chidozie | Sell | 4.1K | $6.03 |
| 2025-12-29 | Ugwumba Chidozie | Sell | 8.1K | $5.95 |
| 2025-12-26 | Ugwumba Chidozie | Sell | 3.4K | $6.32 |
| 2025-12-24 | Ugwumba Chidozie | Sell | 1.5K | $6.27 |
| 2025-12-23 | Ugwumba Chidozie | Sell | 6.8K | $6.27 |
| 2025-12-23 | Ugwumba Chidozie | E | 424K | $0.00 |
| 2025-12-22 | Ugwumba Chidozie | Sell | 4.4K | $6.54 |
| 2025-12-19 | Ugwumba Chidozie | Sell | 5.6K | $6.45 |
| 2025-12-18 | Ugwumba Chidozie | Sell | 5.8K | $6.33 |
| 2025-12-17 | Ugwumba Chidozie | Sell | 2.9K | $6.61 |
| 2025-12-16 | Ugwumba Chidozie | Sell | 7.0K | $6.31 |
| 2025-12-15 | Ugwumba Chidozie | Sell | 11K | $6.49 |
| 2025-12-12 | Ugwumba Chidozie | Sell | 7.6K | $6.79 |
| 2025-12-11 | Ugwumba Chidozie | Sell | 11K | $6.81 |
| 2025-12-10 | Ugwumba Chidozie | Sell | 9.9K | $6.42 |
| 2025-12-09 | Ugwumba Chidozie | Sell | 15K | $5.95 |
| 2025-12-08 | Ugwumba Chidozie | Sell | 21K | $5.70 |
| 2025-12-05 | Ugwumba Chidozie | Sell | 37K | $5.94 |
| 2025-12-04 | Ugwumba Chidozie | Sell | 73K | $6.73 |
| 2025-12-03 | Ugwumba Chidozie | Sell | 57K | $7.86 |
| 2025-08-21 | General Resonance LLC | Sell | 3.4K | $5.34 |
| 2025-06-04 | General Resonance LLC | Sell | 600 | $4.04 |
| 2025-06-02 | General Resonance LLC | Sell | 600 | $4.12 |
| 2025-05-30 | General Resonance LLC | Sell | 410 | $2.80 |
| 2025-05-29 | General Resonance LLC | Sell | 410 | $2.73 |
| 2025-05-28 | General Resonance LLC | Sell | 420 | $2.60 |
| 2025-05-27 | General Resonance LLC | Sell | 420 | $2.45 |
| 2025-03-19 | General Resonance LLC | Sell | 1.4K | $4.40 |
| 2025-03-18 | General Resonance LLC | Sell | 1.3K | $4.45 |
All non-derivative Form 4 activity (SEC), newest first.
Notable events (8-K)
| Date | Items | |
|---|---|---|
| 2026-05-22 | Material agreementExec/director changeShareholder voteExhibits | filing ↗ |
| 2026-05-14 | Material agreementResultsExhibits | filing ↗ |
| 2026-05-05 | Material agreementOtherExhibits | filing ↗ |
| 2026-05-04 | Reg FDOtherExhibits | filing ↗ |
| 2026-03-17 | Material agreementExhibits | filing ↗ |
| 2026-03-12 | ResultsExhibits | filing ↗ |
| 2026-02-24 | OtherExhibits | filing ↗ |
| 2026-01-13 | Material agreementOtherExhibits | filing ↗ |
Recent filings
| Form | Filed | Period | Accession |
|---|---|---|---|
| 8-K | 2026-05-22 | 2026-05-18 | 0001437749-26-018267 ↗ |
| 10-Q | 2026-05-14 | 2026-03-31 | 0001437749-26-016878 ↗ |
| 8-K | 2026-05-14 | 2026-05-11 | 0001437749-26-016881 ↗ |
| 8-K | 2026-05-05 | 2026-05-05 | 0001437749-26-014946 ↗ |
| 8-K | 2026-05-04 | 2026-05-04 | 0001437749-26-014542 ↗ |
| 10-K | 2026-03-17 | 2025-12-31 | 0001437749-26-008502 ↗ |
| 8-K | 2026-03-17 | 2026-03-13 | 0001437749-26-008482 ↗ |
| 8-K | 2026-03-12 | 2026-03-12 | 0001437749-26-007828 ↗ |
| 8-K | 2026-02-24 | 2026-02-24 | 0001437749-26-005156 ↗ |
| 8-K | 2026-01-13 | 2026-01-08 | 0001437749-26-001196 ↗ |
| 8-K | 2026-01-12 | 2026-01-12 | 0001437749-26-001049 ↗ |
| 8-K | 2025-12-03 | 2025-12-03 | 0001437749-25-036713 ↗ |